Targeting a novel cancer-driving protein (LAPTM4B-35) by a small molecule (ETS) to inhibit cancer growth and metastasis.

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Increased levels of LAPTM4B, VEGF and survivin are correlated with tumor progression and poor prognosis in breast cancer patients.

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Q38801879-9FEDE3E5-13AB-4E3E-8C23-55122CC68F87

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Targeting a novel cancer-driving protein (LAPTM4B-35) by a small molecule (ETS) to inhibit cancer growth and metastasis.

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http://www.wikidata.org/entity/Q37629059

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 17 August 2016

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Targeting a novel cancer-drivi ...... cancer growth and metastasis.

@en

Targeting a novel cancer-driving protein

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type

Item

label

Targeting a novel cancer-drivi ...... cancer growth and metastasis.

@en

Targeting a novel cancer-driving protein

@nl

prefLabel

Targeting a novel cancer-drivi ...... cancer growth and metastasis.

@en

Targeting a novel cancer-driving protein

@nl

P1476

Targeting a novel cancer-drivi ...... cancer growth and metastasis.

@en

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Gang Liu

http://www.w3.org/2001/XMLSchema#string

Li Li

http://www.w3.org/2001/XMLSchema#string

Lin Wang

http://www.w3.org/2001/XMLSchema#string

Maojin Li

http://www.w3.org/2001/XMLSchema#string

Rouli Zhou

http://www.w3.org/2001/XMLSchema#string

Yi Shan

http://www.w3.org/2001/XMLSchema#string

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LAPTM4B: a novel cancer-associated gene motivates multidrug resistance through efflux and activating PI3K/AKT signaling

A kinase-independent role for EGF receptor in autophagy initiation

Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer

Role of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: potential prospects for combined targeted therapeutics (review)

Overexpression of LAPTM4B-35: a novel marker of poor prognosis of prostate cancer

Molecular cloning and characterization of LAPTM4B, a novel gene upregulated in hepatocellular carcinoma.

LAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation.

Structure analysis and expressions of a novel tetratransmembrane protein, lysosoma-associated protein transmembrane 4 beta associated with hepatocellular carcinoma.

The human LAPTM4b transcript is upregulated in various types of solid tumours and seems to play a dual functional role during tumour progression.

LAPTM4B-35, a cancer-related gene, is associated with poor prognosis in TNM stages I-III gastric cancer patients.

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58531-58542

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scholarly article

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10.18632/ONCOTARGET.11325

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English

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http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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2016-08-17T00:00:00Z

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27542271

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5295449

http://www.w3.org/2001/XMLSchema#string

Targeting a novel cancer-driving protein (LAPTM4B-35) by a small molecule (ETS) to inhibit cancer growth and metastasis.

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Targeting a novel cancer-driving protein (LAPTM4B-35) by a small molecule (ETS) to inhibit cancer growth and metastasis.

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