Models that include supercoiling of topological domains reproduce several known features of interphase chromosomes.
about
DNA topology and transcriptionChromatin loops as allosteric modulators of enhancer-promoter interactionsActive chromatin and transcription play a key role in chromosome partitioning into topologically associating domains.Simulated binding of transcription factors to active and inactive regions folds human chromosomes into loops, rosettes and topological domains.Protein/DNA interactions in complex DNA topologies: expect the unexpectedThe role of loops on the order of eukaryotes and prokaryotesPhysical mechanisms behind the large scale features of chromatin organizationTwo ways to fold the genome during the cell cycle: insights obtained with chromosome conformation captureHi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization.CTCF and cohesin regulate chromatin loop stability with distinct dynamics.Effects of supercoiling on enhancer-promoter contacts.Effects of physiological self-crowding of DNA on shape and biological properties of DNA molecules with various levels of supercoiling.The Hitchhiker's guide to Hi-C analysis: practical guidelines.Perspectives: using polymer modeling to understand the formation and function of nuclear compartments.Formation of Chromosomal Domains by Loop Extrusion.Protein/DNA interactions in complex DNA topologies: expect the unexpected.Modeling chromosomes: Beyond pretty pictures.Gene regulation during development in the light of topologically associating domains.Simulating topological domains in human chromosomes with a fitting-free model.Genomic Energy Landscapes.Modelling genome-wide topological associating domains in mouse embryonic stem cells.Unraveling the mechanisms of chromatin fibril packagingTranscription-induced supercoiling explains formation of self-interacting chromatin domains in S. pombe.Topological constraints strongly affect chromatin reconstitution in silico.The Three-Dimensional Organization of Mammalian Genomes.Recent evidence that TADs and chromatin loops are dynamic structures.Molecular simulations of cellular processes.Combined collapse by bridging and self-adhesion in a prototypical polymer model inspired by the bacterial nucleoid.A maximum-entropy model for predicting chromatin contacts.Transcription-induced supercoiling as the driving force of chromatin loop extrusion during formation of TADs in interphase chromosomes.Polymer Physics of the Large-Scale Structure of Chromatin.DNA Supercoiling, Topoisomerases, and Cohesin: Partners in Regulating Chromatin Architecture?Shape Transitions and Chiral Symmetry Breaking in the Energy Landscape of the Mitotic Chromosome.Looping probability of random heteropolymers helps to understand the scaling properties of biopolymers.How epigenome drives chromatin folding and dynamics, insights from efficient coarse-grained models of chromosomes.3D modeling of chromatin structure: is there a way to integrate and reconcile single cell and population experimental data?Dense neural networks for predicting chromatin conformationPolymer models of the organization of chromosomes in the nucleus of cells
P2860
Q26865092-5B8D6F33-6580-4954-B315-BA923DF0313DQ27320948-32F26813-3335-4848-8B77-C1266C99035DQ27321750-644C5709-313E-43AA-B193-6239B449C44CQ27324074-D503268E-948A-4E81-BE1B-9F8D23479048Q28073043-BD624157-F6F8-41D0-963B-84FDF15BE683Q28081349-A4FE345C-4338-4691-9C63-7326C0B50D7FQ28086968-3F35DE3E-856A-40A3-A646-106611C17CDBQ29300664-2B853EBB-A372-4C2B-9DAE-A9E132B859ACQ30826585-888A8539-3FDE-4AB5-8545-DF1832DE48B0Q33732376-3D1C7B22-822C-45A2-B32D-D7B53C9CE583Q34249611-6E389FE5-EC75-4E80-A12E-D195BE4C963EQ35131103-DF0D1C4A-712F-48BA-BB95-D9726BAD6A28Q35140940-27C3EEB9-38FA-4685-90A9-67BEE34532D0Q36250466-7FAB4324-4ED2-4233-B497-3AC2448C7FB8Q36957773-E8C4864F-618E-4F10-9358-A1BDA402B7FBQ37497864-BD1ECE4F-308C-41AE-91E3-5F2AF7016206Q38585877-B3A59B69-3770-4B6B-9C20-6DAB561A21EBQ38630582-F70A2CE0-0A8B-4C06-8DB7-48C4767393A6Q38731139-DB255AC0-A110-4E82-AA7F-E309433A1A55Q38969583-B3529009-BE5D-4853-A798-8EBB63A4FA89Q39008686-CBCDD947-9417-43D9-B0C9-09E783FE64A3Q39718691-933996D2-1586-4B3E-8B03-4C10ADB9A24CQ42163298-3491E91C-81A6-4019-9061-3EC0EB8EFC32Q43097658-03F8AB09-2DF6-4ADD-AE99-0403F4E37146Q46383154-772C871A-27C2-4261-A56F-D457121AAF04Q46814626-61BE9DF4-7A08-4DC0-8192-6EE90E1CC9E1Q47135560-E402A94B-1E6C-4013-9D5A-845BA96E4AA3Q47694001-28DB03B2-C969-496C-9CB8-E5A374D3E9DCQ48105797-B1BB8605-29B8-4C4E-B68A-7F16616B5F44Q50000204-C05BFEF0-CF7E-4072-8297-F0A5B1A28D32Q51471995-88E2DAEA-3B0B-4DBD-B3E7-DFB6303C8E13Q52652232-501CA59E-DEFA-4A9A-BDF6-DB02306E9537Q52861638-5E55A06F-05E0-4FD3-86E4-1D2AD8EAB13CQ52883037-821F1C20-6F16-4F8C-8BBA-FF6598A344FCQ55341628-5A55DA48-2D11-47E0-8587-2B23B45E31D0Q57231673-26DE6347-EDB0-4829-9FD7-9FE17918CBC5Q57474560-4893B5C0-2C4E-4475-884F-1618A8080C35Q59123236-6687AC3F-9F2E-443D-AFCC-884E0BAB800B
P2860
Models that include supercoiling of topological domains reproduce several known features of interphase chromosomes.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 December 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Models that include supercoili ...... res of interphase chromosomes.
@en
Models that include supercoili ...... res of interphase chromosomes.
@nl
type
label
Models that include supercoili ...... res of interphase chromosomes.
@en
Models that include supercoili ...... res of interphase chromosomes.
@nl
prefLabel
Models that include supercoili ...... res of interphase chromosomes.
@en
Models that include supercoili ...... res of interphase chromosomes.
@nl
P2860
P50
P356
P1476
Models that include supercoili ...... res of interphase chromosomes.
@en
P2093
Andrzej Stasiak
P2860
P304
P356
10.1093/NAR/GKT1353
P407
P577
2013-12-23T00:00:00Z