RhoA/Rho-kinase: pathophysiologic and therapeutic implications in gastrointestinal smooth muscle tone and relaxation.
about
Adenosine analogue-oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIalpha)Altered expression pattern of molecular factors involved in colonic smooth muscle functions: an immunohistochemical study in patients with diverticular disease.Role of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone.Aging-associated oxidative stress leads to decrease in IAS tone via RhoA/ROCK downregulationRole of PKC and RhoA/ROCK pathways in the spontaneous phasic activity in the rectal smooth muscle.Tonic and phasic smooth muscle contraction is not regulated by the PKCα - CPI-17 pathway in swine stomach antrum and fundusRole of rho kinase in the functional and dysfunctional tonic smooth muscles.Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cellsRegulation of basal LC20 phosphorylation by MYPT1 and CPI-17 in murine gastric antrum, gastric fundus, and proximal colon smooth muscles.Nature of extracellular signal that triggers RhoA/ROCK activation for the basal internal anal sphincter tone in humans.RhoA/ROCK pathway is the major molecular determinant of basal tone in intact human internal anal sphincterBimodal effect of oxidative stress in internal anal sphincter smooth muscle.Bioengineered human IAS reconstructs with functional and molecular properties similar to intact IASRole of microRNAs in gastrointestinal smooth muscle fibrosis and dysfunction: novel molecular perspectives on the pathophysiology and therapeutic targeting.Impaired contractile responses and altered expression and phosphorylation of Ca(2+) sensitization proteins in gastric antrum smooth muscles from ob/ob mice.3-Hydroxymethyl coenzyme A reductase inhibition attenuates spontaneous smooth muscle tone via RhoA/ROCK pathway regulated by RhoA prenylationGastrointestinal tone; its genesis and contribution to the physical processes of digestion.Gastric and pyloric sphincter muscle function and the developmental-dependent regulation of gastric content emptying in the rat.Basal internal anal sphincter tone, inhibitory neurotransmission, and other factors contributing to the maintenance of high pressures in the anal canal.Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133aSmooth muscle-specific myosin phosphatase target subunit 1 (MYPT1): an important piece of the puzzle.Infantile hypertrophic pyloric stenosis (IHPS): a study of its pathophysiology utilizing the newborn hph-1 mouse model of the disease.The newborn rat gastric emptying rate is volume and not developmentally dependent.Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone.Rhos and Rho kinases in the rat prostate: their possible functional roles and distributions.
P2860
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P2860
RhoA/Rho-kinase: pathophysiologic and therapeutic implications in gastrointestinal smooth muscle tone and relaxation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
RhoA/Rho-kinase: pathophysiolo ...... th muscle tone and relaxation.
@en
RhoA/Rho-kinase: pathophysiolo ...... th muscle tone and relaxation.
@nl
type
label
RhoA/Rho-kinase: pathophysiolo ...... th muscle tone and relaxation.
@en
RhoA/Rho-kinase: pathophysiolo ...... th muscle tone and relaxation.
@nl
prefLabel
RhoA/Rho-kinase: pathophysiolo ...... th muscle tone and relaxation.
@en
RhoA/Rho-kinase: pathophysiolo ...... th muscle tone and relaxation.
@nl
P2860
P1433
P1476
RhoA/Rho-kinase: pathophysiolo ...... th muscle tone and relaxation.
@en
P2093
Benjamin R Phillips
Pinckney J Maxwell
P2860
P304
P356
10.1053/J.GASTRO.2009.11.016
P407
P577
2009-11-23T00:00:00Z