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Genetic resistance to scrapie infection in experimentally challenged goats

Genetic resistance to scrapie infection in experimentally challenged goats

http://www.wikidata.org/entity/Q37644091

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Review: A review on classical and atypical scrapie in caprine: Prion protein gene polymorphisms and their role in the disease.Perspectives of a scrapie resistance breeding scheme targeting Q211, S146 and K222 caprine PRNP alleles in Greek goats.Identification of amino acid variation in the prion protein associated with classical scrapie in Canadian dairy goats Scrapie incidence and PRNP polymorphisms: rare small ruminant breeds of Sicily with TSE protecting genetic reservoirs.Genetic and Pathological Follow-Up Study of Goats Experimentally and Naturally Exposed to a Sheep Scrapie Isolate.Prion protein genotype survey confirms low frequency of scrapie-resistant K222 allele in British goat herds.Role of the goat K222-PrP(C) polymorphic variant in prion infection resistance The transmissible spongiform encephalopathies of livestock.A cross-sectional study of PRNP gene in two native Sicilian goat populations in Italy: a relation between prion gene polymorphisms and scrapie incidence.Caprine PrP variants harboring Asp-146, His-154 and Gln-211 alleles display reduced convertibility upon interaction with pathogenic murine prion protein in scrapie infected cells.A transfectant RK13 cell line permissive to classical caprine scrapie prion propagation The effect of polymorphisms at codon 146 of the goat PRNP gene on susceptibility to challenge with classical scrapie by different routes.Low fraction of the 222K PrP variant in the protease-resistant moiety of PrPres in heterozygous scrapie positive goats.Immunolabelling of non-phosphorylated neurofilament indicates damage of spinal cord axons in TSE-infected goats.Sensitive and specific detection of classical scrapie prions in the brains of goats by real-time quaking-induced conversion.Goat K222-PrP(C) polymorphic variant does not provide resistance to atypical scrapie in transgenic mice.Role of the PRNP S127 allele in experimental infection of goats with classical caprine scrapie.Effect of Q211 and K222 PRNP Polymorphic Variants in the Susceptibility of Goats to Oral Infection With Goat Bovine Spongiform Encephalopathy.Protecting effect of PrP codons M142 and K222 in goats orally challenged with bovine spongiform encephalopathy prions.Genetic resistance to transmissible spongiform encephalopathies (TSE) in goats PRNP variants in goats reduce sensitivity of detection of PrP(Sc) by immunoassay.Predicting the impact of selection for scrapie resistance on PRNP genotype frequencies in goats.Genetic profile of scrapie codons 146, 211 and 222 in the PRNP gene locus in three breeds of dairy goats.Low-volume goat milk transmission of classical scrapie to lambs and goat kids

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P2860

Genetic resistance to scrapie infection in experimentally challenged goats

http://www.wikidata.org/entity/Q37644091

description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年學術文章

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2013年學術文章

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2013年學術文章

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name

Genetic resistance to scrapie infection in experimentally challenged goats

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Genetic resistance to scrapie infection in experimentally challenged goats.

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type

label

Genetic resistance to scrapie infection in experimentally challenged goats

@en

Genetic resistance to scrapie infection in experimentally challenged goats.

@nl

prefLabel

Genetic resistance to scrapie infection in experimentally challenged goats

@en

Genetic resistance to scrapie infection in experimentally challenged goats.

@nl

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Journal of Virology

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Genetic resistance to scrapie infection in experimentally challenged goats

@en

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Caroline Lacroux

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Cécile Perrin-Chauvineau

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Fabien Corbière

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Francis Barillet

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François Schelcher

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Isabelle Brémaud

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Naima Aron

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Olivier Andréoletti

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Patricia Aguilar-Calvo

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Pierrette Costes

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P2860

Resistance to classical scrapie in experimentally challenged goats carrying mutation K222 of the prion protein gene.

The prevalence of atypical scrapie in sheep from positive flocks is not higher than in the general sheep population in 11 European countries.

Scrapie prevalence in sheep of susceptible genotype is declining in a population subject to breeding for resistance.

Classic scrapie in sheep with the ARR/ARR prion genotype in Germany and France.

Atypical/Nor98 scrapie infectivity in sheep peripheral tissues.

Clinical signs, histopathology and genetics of experimental transmission of BSE and natural scrapie to sheep and goats.

Breeding with resistant rams leads to rapid control of classical scrapie in affected sheep flocks.

A descriptive study of the prevalence of atypical and classical scrapie in sheep in 20 European countries

Atypical/Nor98 scrapie: properties of the agent, genetics, and epidemiology.

Progress and limits of PrP gene selection policy.

P304

2406-2413

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scholarly article

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10.1128/JVI.02872-13

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5

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88

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Juan Maria Torres

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2013-11-27T00:00:00Z

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24284317

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3958109

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