Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes. - Wikidata - wikimedia - TriplyDB

Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes.

Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes.

http://www.wikidata.org/entity/Q37649062

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Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic Landscapes Cohesin mutations in myeloid malignancies: underlying mechanisms Complete loss of STAG2 expression is an indicator of good prognosis in patients with bladder cancer.Cohesin gene mutations in tumorigenesis: from discovery to clinical significance STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments.Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations.Molecular biology of bladder cancer.Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2.Genomic Copy Number Variation Affecting Genes Involved in the Cell Cycle Pathway: Implications for Somatic Mosaicism.The three-dimensional cancer genome.Cohesin in cancer: chromosome segregation and beyond.Molecular biology of bladder cancer: new insights into pathogenesis and clinical diversity.The role of genomics in the management of advanced bladder cancer.Genome stability: What we have learned from cohesinopathies.Cohesin mutations in human cancer Genetic Alterations in the Molecular Subtypes of Bladder Cancer: Illustration in the Cancer Genome Atlas Dataset.The Role of Aneuploidy in Cancer Evolution.Next-generation Sequencing of Nonmuscle Invasive Bladder Cancer Reveals Potential Biomarkers and Rational Therapeutic Targets.Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts.Towards a Next-Generation Sequencing Diagnostic Service for Tumour Genotyping: A Comparison of Panels and Platforms.Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency.Loss of Stromal Antigen 2 (STAG2) Expression in Upper Urinary Tract Carcinoma: Differential Prognostic Effect According to the Ki-67 Proliferating Index.Bladder cancer.

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Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes.

http://www.wikidata.org/entity/Q37649062

description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年學術文章

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2013年學術文章

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2013年學術文章

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Frequent inactivating mutation ...... romosomal copy number changes.

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Frequent inactivating mutation ...... romosomal copy number changes.

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Frequent inactivating mutation ...... romosomal copy number changes.

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Frequent inactivating mutation ...... romosomal copy number changes.

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Frequent inactivating mutation ...... romosomal copy number changes.

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Frequent inactivating mutation ...... romosomal copy number changes.

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Frequent inactivating mutation ...... romosomal copy number changes.

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Frequent inactivating mutation ...... romosomal copy number changes.

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Frequent inactivating mutation ...... romosomal copy number changes.

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Human Molecular Genetics

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Frequent inactivating mutation ...... romosomal copy number changes.

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Carolyn D Hurst

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Claire F Taylor

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Fiona M Platt

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Helene H Thygesen

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P2860

Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.

A unique role of cohesin-SA1 in gene regulation and development

Evidence of a transcriptional co-activator function of cohesin STAG/SA/Scc3.

Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.

Nuclear import and export signals of human cohesins SA1/STAG1 and SA2/STAG2 expressed in Saccharomyces cerevisiae

Cohesin: genomic insights into controlling gene transcription and development

Specific sites in the C terminus of CTCF interact with the SA2 subunit of the cohesin complex and are required for cohesin-dependent insulation activity

Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors

Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres.

Mutational inactivation of STAG2 causes aneuploidy in human cancer

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1964-1974

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10.1093/HMG/DDT589

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8

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23

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Margaret A Knowles

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2013-11-22T00:00:00Z

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258854219

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24270882

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3959811

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