MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.
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MICU1 drives glycolysis and chemoresistance in ovarian cancer.MICU1 may be a promising intervention target for gut-derived sepsis induced by intra-abdominal hypertension.The Function of the Mitochondrial Calcium Uniporter in Neurodegenerative Disorders.The In Vivo Biology of the Mitochondrial Calcium Uniporter.Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes.New insights into the role of mitochondrial calcium homeostasis in cell migration.Intracellular Ca2+ Sensing: Its Role in Calcium Homeostasis and Signaling.Structure, Activity Regulation, and Role of the Mitochondrial Calcium Uniporter in Health and Disease.Role of mitochondrial dysfunction and dysregulation of Ca2+ homeostasis in the pathophysiology of insulin resistance and type 2 diabetes.The path from mitochondrial ROS to aging runs through the mitochondrial permeability transition pore.Pathological consequences of MICU1 mutations on mitochondrial calcium signalling and bioenergetics.Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter.Proteolytic control of the mitochondrial calcium uniporter complex.Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle.Mitochondrial Ca2+ transport in the endothelium: regulation by ions, redox signalling and mechanical forces.Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity.MICU2 Restricts Spatial Crosstalk between InsP3R and MCU Channels by Regulating Threshold and Gain of MICU1-Mediated Inhibition and Activation of MCU.The mitochondrial calcium uniporter complex in trypanosomes.Pharmacological modulation of mitochondrial calcium homeostasis.High-affinity cooperative Ca2+ binding by MICU1-MICU2 serves as an on-off switch for the uniporter.New Insights in Cardiac Calcium Handling and Excitation-Contraction Coupling.The emerging role of immune dysfunction in mitochondrial diseases as a paradigm for understanding immunometabolism.m-AAA proteases, mitochondrial calcium homeostasis and neurodegeneration.Mitochondrial Calcium Handling in Physiology and Disease.Emerging molecular mechanisms in chemotherapy: Ca2+ signaling at the mitochondria-associated endoplasmic reticulum membranes.Restoring mitochondrial calcium uniporter expression in diabetic mouse heart improves mitochondrial calcium handling and cardiac function.The Influence of MicroRNAs on Mitochondrial CalciumFOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiationParvalbumin alters mitochondrial dynamics and affects cell morphologyCryo-EM structure of a fungal mitochondrial calcium uniporter
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MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 July 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.
@en
MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.
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type
label
MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.
@en
MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.
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prefLabel
MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.
@en
MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.
@nl
P2093
P2860
P1433
P1476
MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload.
@en
P2093
Charles Halsey
Chengyu Liu
Danielle A Springer
Elizabeth Murphy
Julia C Liu
Maria M Fergusson
Randi J Parks
Sara Menazza
Toren Finkel
P2860
P304
P356
10.1016/J.CELREP.2016.07.011
P577
2016-07-27T00:00:00Z