The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis.
about
Wnt5a Signaling in CancerWNT-5A: signaling and functions in health and diseaseTherapy for BRAFi-Resistant Melanomas: Is WNT5A the Answer?The role of Ryk and Ror receptor tyrosine kinases in Wnt signal transductionPathways and therapeutic targets in melanomaIntegrated Conformational and Lipid-Sensing Regulation of Endosomal ArfGEF BRAG2Wnt Signaling in Cell Motility and Invasion: Drawing Parallels between Development and CancerARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal MelanomaThe BRAG/IQSec family of Arf GEFs.EGF-reduced Wnt5a transcription induces epithelial-mesenchymal transition via Arf6-ERK signaling in gastric cancer cells.Challenging role of Wnt5a and its signaling pathway in cancer metastasis (Review).A river runs through it: how autophagy, senescence, and phagocytosis could be linked to phospholipase D by Wnt signalingAttacking the supply wagons to starve cancer cells to death.SLIT/ROBO2 signaling promotes mammary stem cell senescence by inhibiting Wnt signaling.ARF6 inhibition stabilizes the vasculature and enhances survival during endotoxic shock.lincRNA-RoR and miR-145 regulate invasion in triple-negative breast cancer via targeting ARF6.Molecular Role of RNF43 in Canonical and Noncanonical Wnt SignalingStructure-activity relationship studies of QS11, a small molecule Wnt synergistic agonist.Pdlim7 Regulates Arf6-Dependent Actin Dynamics and Is Required for Platelet-Mediated Thrombosis in Mice.BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistanceEndothelial Robo4 suppresses breast cancer growth and metastasis through regulation of tumor angiogenesisEnhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals.ARF6-regulated endocytosis of growth factor receptors links cadherin-based adhesion to canonical Wnt signaling in epitheliaHypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.The biology of uveal melanomaA Wnt-er migration: the confusing role of β-catenin in melanoma metastasis.Melanoma metastasis: new concepts and evolving paradigms.Why is melanoma so metastatic?Developmental pathways activated in melanocytes and melanoma.Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance.Targeting the WNT Signaling Pathway in Cancer Therapeutics.The Wnts of change: How Wnts regulate phenotype switching in melanoma.WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolismA Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib.Wnt5a inhibited human trophoblast cell line HTR8/SVneo invasion: implications for early placentation and preeclampsia.The role of thioredoxin reductase 1 in melanoma metabolism and metastasis.The WNT-less wonder: WNT-independent β-catenin signaling.Interleukin-6 drives melanoma cell motility through p38α-MAPK-dependent up-regulation of WNT5A expression.Pathological functions of the small GTPase Arf6 in cancer progression: Tumor angiogenesis and metastasis.Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo.
P2860
Q26738408-9FBEF056-8E6E-45A3-B8A6-A4EA7C5DA37DQ26777942-73E08482-9B05-42B9-BB74-1F82A096A362Q26782222-407553E0-A15E-4677-A331-B560E640C81DQ26852972-E427D325-418C-4087-A4E3-95419CC9AECEQ26865736-A4CFB057-FDAB-4043-A68D-16916FD0CDA1Q27680018-E85EFB06-921D-4F7B-8E29-4A1D25822290Q28077330-B7821826-D923-49F8-A81D-5424E9CF78AAQ28115305-5B02BC85-74B2-4B41-A0CA-3FD216E413A7Q30275740-58DE076D-F3DB-4729-8479-63F0B9F34E11Q30384677-C19D099C-B749-4FEB-9F05-E43196DB7198Q33769672-EDBF0A09-390F-4129-B4AF-7139F2BEE42EQ34341405-5A24DBCC-3E26-473E-8FF9-163A6C6B41A2Q34516773-F1DF16F1-4AA1-4145-87D4-FD5EF676F417Q34699735-D9E1555C-007B-4ED8-AFD2-61E3684E6540Q34917691-FCA4A0C7-9F1B-4FF8-9DAE-783CF33B3C2DQ35108871-1C4D32AC-8CAC-4397-925A-3CD552FA5341Q35573020-D407CFF9-16C8-4404-9BFD-34B163D5464CQ36167110-3338E1A7-7996-4AC8-AE38-92DF9B43621EQ36177152-60306ED2-C3B2-4AC3-AC2A-CDE77EB26098Q36432043-EDD72E4D-16BC-4078-AB11-5DD40BBE3633Q36539110-780F9852-DF09-45A2-98F7-5B34266439DDQ36957310-5BD42BB2-50CA-47BD-A646-BAB76FFACBDDQ37036357-D3707BDD-32A6-4718-BFCB-DED86D7DC905Q37570262-107BA56B-ABE9-452E-804D-8CCF640BECC6Q37742632-8C84BA73-92C4-4DEC-A758-94F82BBB6C1AQ38093429-9487CA8A-45B4-4295-B4F3-94B3DDC3E42AQ38111220-EA2B99E1-DEBE-4DB4-9B86-6D8E5C377C2AQ38150869-CB6FE0BB-8CB4-4ECA-A446-6ED12CB36FE3Q38238576-E131700F-DAEC-4759-B220-B5ACB27026CBQ38385463-A619AE8D-4C4C-43FE-B06C-CCD28EA853E4Q38573776-9CD6F604-C8E4-43AE-98FE-891408A60BC2Q38627456-CD1D4CC5-6C28-4903-945D-408805251675Q38628775-97ED2FE3-C56F-49BD-BC71-E6654BCAD815Q38757495-E30B0CF2-B9C1-4B81-89D5-7640F26EC552Q38795141-CA03F730-9FEB-41A2-9893-3B72080A8DFEQ38851918-56BBBA2C-D2D7-4B23-904C-A36CFE266B06Q38867422-6513FFD9-913E-473A-9E5D-3CD77CEBF1ECQ38982133-5E0DAB46-F449-4361-9A31-042237400059Q42088910-E09460CB-A346-41B1-A16A-FE5007E4AF9BQ46380429-621EFA6B-BF90-41DD-9BFA-0A1D8C7710E2
P2860
The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 05 March 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.
@en
The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.
@nl
type
label
The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.
@en
The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.
@nl
prefLabel
The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.
@en
The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.
@nl
P2093
P2860
P1433
P1476
The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.
@en
P2093
Aaron Rogers
Alanna Sedgwick
Allie H Grossmann
Crislyn D'Souza-Schorey
Jae Hyuk Yoo
James Clancy
Kenneth F Grossmann
Kirill Ostanin
Kirk R Thomas
P2860
P356
10.1126/SCISIGNAL.2003398
P577
2013-03-05T00:00:00Z