The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis. - Wikidata - wikimedia - TriplyDB

The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis.

The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis.

http://www.wikidata.org/entity/Q37651978

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Wnt5a Signaling in Cancer WNT-5A: signaling and functions in health and disease Therapy for BRAFi-Resistant Melanomas: Is WNT5A the Answer?The role of Ryk and Ror receptor tyrosine kinases in Wnt signal transduction Pathways and therapeutic targets in melanoma Integrated Conformational and Lipid-Sensing Regulation of Endosomal ArfGEF BRAG2 Wnt Signaling in Cell Motility and Invasion: Drawing Parallels between Development and Cancer ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma The BRAG/IQSec family of Arf GEFs.EGF-reduced Wnt5a transcription induces epithelial-mesenchymal transition via Arf6-ERK signaling in gastric cancer cells.Challenging role of Wnt5a and its signaling pathway in cancer metastasis (Review).A river runs through it: how autophagy, senescence, and phagocytosis could be linked to phospholipase D by Wnt signaling Attacking the supply wagons to starve cancer cells to death.SLIT/ROBO2 signaling promotes mammary stem cell senescence by inhibiting Wnt signaling.ARF6 inhibition stabilizes the vasculature and enhances survival during endotoxic shock.lincRNA-RoR and miR-145 regulate invasion in triple-negative breast cancer via targeting ARF6.Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling Structure-activity relationship studies of QS11, a small molecule Wnt synergistic agonist.Pdlim7 Regulates Arf6-Dependent Actin Dynamics and Is Required for Platelet-Mediated Thrombosis in Mice.BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance Endothelial Robo4 suppresses breast cancer growth and metastasis through regulation of tumor angiogenesis Enhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals.ARF6-regulated endocytosis of growth factor receptors links cadherin-based adhesion to canonical Wnt signaling in epithelia Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.The biology of uveal melanoma A Wnt-er migration: the confusing role of β-catenin in melanoma metastasis.Melanoma metastasis: new concepts and evolving paradigms.Why is melanoma so metastatic?Developmental pathways activated in melanocytes and melanoma.Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance.Targeting the WNT Signaling Pathway in Cancer Therapeutics.The Wnts of change: How Wnts regulate phenotype switching in melanoma.WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolism A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib.Wnt5a inhibited human trophoblast cell line HTR8/SVneo invasion: implications for early placentation and preeclampsia.The role of thioredoxin reductase 1 in melanoma metabolism and metastasis.The WNT-less wonder: WNT-independent β-catenin signaling.Interleukin-6 drives melanoma cell motility through p38α-MAPK-dependent up-regulation of WNT5A expression.Pathological functions of the small GTPase Arf6 in cancer progression: Tumor angiogenesis and metastasis.Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo.

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The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis.

http://www.wikidata.org/entity/Q37651978

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 05 March 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.

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The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.

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The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.

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The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.

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prefLabel

The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.

@en

The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.

@nl

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SCISIGNAL.2003398

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Science Signaling

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The small GTPase ARF6 stimulat ...... anoma invasion and metastasis.

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Aaron Rogers

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Alanna Sedgwick

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Allie H Grossmann

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Crislyn D'Souza-Schorey

http://www.w3.org/2001/XMLSchema#string

Dean Y Li

http://www.w3.org/2001/XMLSchema#string

Jae Hyuk Yoo

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James Clancy

http://www.w3.org/2001/XMLSchema#string

Kenneth F Grossmann

http://www.w3.org/2001/XMLSchema#string

Kirill Ostanin

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Kirk R Thomas

http://www.w3.org/2001/XMLSchema#string

P2860

FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity

Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

A member of the Frizzled protein family mediating axis induction by Wnt-5A

Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

ARF-GEP(100), a guanine nucleotide-exchange protein for ADP-ribosylation factor 6

Microvesicles: mediators of extracellular communication during cancer progression

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10.1126/SCISIGNAL.2003398

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265

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6

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2013-03-05T00:00:00Z

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3961043

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