Yeast unfolds the road map toward alpha-synuclein-induced cell death.
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C-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease.Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent mannerHigh expression levels of the D686N Parkinson's disease mutation in VPS35 induces α-synuclein-dependent toxicity in yeastUbiquitinylation of α-synuclein by carboxyl terminus Hsp70-interacting protein (CHIP) is regulated by Bcl-2-associated athanogene 5 (BAG5).Dexamethasone induces the expression of LRRK2 and α-synuclein, two genes that when mutated cause Parkinson's disease in an autosomal dominant manner.Untangling the Roles of Anti-Apoptosis in Regulating Programmed Cell Death using Humanized Yeast Cells.A powerful yeast model to investigate the synergistic interaction of α-synuclein and tau in neurodegeneration.Mammalian ribosomal and chaperone protein RPS3A counteracts α-synuclein aggregation and toxicity in a yeast model system.Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease.Protein expression regulation under oxidative stress.Oxidative stress and programmed cell death in yeast.Enhanced J-protein interaction and compromised protein stability of mtHsp70 variants lead to mitochondrial dysfunction in Parkinson's diseaseP73 and age-related diseases: is there any link with Parkinson Disease?Aggresome formation and segregation of inclusions influence toxicity of α-synuclein and synphilin-1 in yeast.Using yeast models to probe the molecular basis of amyotrophic lateral sclerosis.Posttranslational Modifications and Clearing of α-Synuclein Aggregates in YeastRafts, Nanoparticles and Neural DiseaseA yeast model for amyloid-β aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity.Human Thyroid Cancer-1 (TC-1) is a vertebrate specific oncogenic protein that protects against copper and pro-apoptotic genes in yeast.Yeast as a model system to study tau biology.Interplay between sumoylation and phosphorylation for protection against α-synuclein inclusions.SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy.The Impact of ESCRT on Aβ Induced Membrane Lesions in a Yeast Model for Alzheimer's Disease
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Yeast unfolds the road map toward alpha-synuclein-induced cell death.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 December 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Yeast unfolds the road map toward alpha-synuclein-induced cell death.
@en
Yeast unfolds the road map toward alpha-synuclein-induced cell death.
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Yeast unfolds the road map toward alpha-synuclein-induced cell death.
@en
Yeast unfolds the road map toward alpha-synuclein-induced cell death.
@nl
prefLabel
Yeast unfolds the road map toward alpha-synuclein-induced cell death.
@en
Yeast unfolds the road map toward alpha-synuclein-induced cell death.
@nl
P2093
P2860
P356
P1476
Yeast unfolds the road map toward alpha-synuclein-induced cell death.
@en
P2093
J Anandhakumar
J Winderickx
T Vanhelmont
V Franssens
P2860
P2888
P304
P356
10.1038/CDD.2009.203
P577
2009-12-18T00:00:00Z