Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.
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Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.Rare variants in fox-1 homolog A (RBFOX1) are associated with lower blood pressure.Prediction of gene expression with cis-SNPs using mixed models and regularization methodsAn Exploration of Gene-Gene Interactions and Their Effects on HypertensionRenal sodium handling and sodium sensitivityComparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits.Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.Concepts, estimation and interpretation of SNP-based heritability.Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: a multi-cohort analysis.Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.Complement Factor B Is a Determinant of Both Metabolic and Cardiovascular Features of Metabolic Syndrome.Genetic association studies in cardiovascular diseases: Do we have enough power?A Review of the Genetics of Hypertension with a Focus on Gene-Environment Interactions.Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.Are genetic polymorphisms in the renin-angiotensin-aldosterone system associated with essential hypertension? Evidence from genome-wide association studies.Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.Catechol-O-Methyltransferase (COMT): An Update on Its Role in Cancer, Neurological and Cardiovascular Diseases.Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos.Beyond gut feelings: how the gut microbiota regulates blood pressure.Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry.Hypertension: From GWAS to functional genomics-based precision medicine.Alterations of the Gut Microbiome in Hypertension.Genetic analysis of deep phenotyping projects in common disorders.Admixture mapping in the Hispanic Community Health Study/Study of Latinos reveals regions of genetic associations with blood pressure traits.DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation.Epigenome-wide association studies identify DNA methylation associated with kidney function.Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.Weighted functional linear regression models for gene-based association analysis.Power Analysis for Genetic Association Test (PAGEANT) provides insights to challenges for rare variant association studies.Genetic mechanisms of human hypertension and their implications for blood pressure physiology.Towards precision nephrology: the opportunities and challenges of genomic medicine.Chronic disease research in Europe and the need for integrated population cohorts.A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.Bevacizumab-induced hypertension: Clinical presentation and molecular understanding.Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases.Advances in the Genetics of Hypertension: The Effect of Rare Variants.Cardiovascular disease: The rise of the genetic risk score.Integrative Bioinformatics Approaches for Identification of Drug Targets in Hypertension.Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
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Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 September 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Meta-analysis identifies commo ...... ing with metabolic trait loci.
@en
Meta-analysis identifies commo ...... ing with metabolic trait loci.
@nl
type
label
Meta-analysis identifies commo ...... ing with metabolic trait loci.
@en
Meta-analysis identifies commo ...... ing with metabolic trait loci.
@nl
prefLabel
Meta-analysis identifies commo ...... ing with metabolic trait loci.
@en
Meta-analysis identifies commo ...... ing with metabolic trait loci.
@nl
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P2860
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Meta-analysis identifies commo ...... ing with metabolic trait loci.
@en
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Adolfo Correa
Aldi T Kraja
Alexander P Reiner
Aravinda Chakravarti
Arend Voorman
Audrey Y Chu
Ayush Giri
CHD Exome+ Consortium
CKDGen Consortium
Christopher J O'Donnell
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P2888
P304
P356
10.1038/NG.3660
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P50
P577
2016-09-12T00:00:00Z