HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression.
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Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancerEpigenetic reprogramming of HOXC10 in endocrine-resistant breast cancerExpression signatures of HOX cluster genes in cervical cancer pathogenesis: Impact of human papillomavirus type 16 oncoprotein E7Metastatic triple-negative breast cancer patient with TP53 tumor mutation experienced 11 months progression-free survival on bortezomib monotherapy without adverse events after ending standard treatments with grade 3 adverse events.High-level expression of HOXB13 is closely associated with tumor angiogenesis and poor prognosis of hepatocellular carcinomaDysregulation of the homeobox transcription factor gene HOXB13: role in prostate cancer.HOX genes and their role in the development of human cancers.HOXB5 Promotes the Proliferation and Invasion of Breast Cancer Cells.Acquisition of epithelial-mesenchymal transition phenotype in the tamoxifen-resistant breast cancer cell: a new role for G protein-coupled estrogen receptor in mediating tamoxifen resistance through cancer-associated fibroblast-derived fibronectin aHOXB13 overexpression is an independent predictor of early PSA recurrence in prostate cancer treated by radical prostatectomyDNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer.Overexpression of homeobox B-13 correlates with angiogenesis, aberrant expression of EMT markers, aggressive characteristics and poor prognosis in pancreatic carcinomaHOXB13 and ALX4 induce SLUG expression for the promotion of EMT and cell invasion in ovarian cancer cells.HOXB7 Is an ERα Cofactor in the Activation of HER2 and Multiple ER Target Genes Leading to Endocrine Resistance.HOXB7-S3 inhibits the proliferation and invasion of MCF-7 human breast cancer cells.Analysis of gene expression of secreted factors associated with breast cancer metastases in breast cancer subtypes.HOX genes: Major actors in resistance to selective endocrine response modifiers.Recurrent HOXB13 mutations in the Dutch population do not associate with increased breast cancer risk.Beta protein 1 homeoprotein induces cell growth and estrogen-independent tumorigenesis by binding to the estrogen receptor in breast cancer.Two-gene expression ratio as predictor for breast cancer treated with tamoxifen: evidence from meta-analysis.Homeodomain-containing gene 10 inhibits cell apoptosis and promotes cell invasion and migration in osteosarcoma cell lines.The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma.Increased copy number of the DLX4 homeobox gene in breast axillary lymph node metastasis.HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells.Increased HOXC6 expression predicts chemotherapy sensitivity in patients with esophageal squamous cell carcinoma.Oncoprotein HBXIP enhances HOXB13 acetylation and co-activates HOXB13 to confer tamoxifen resistance in breast cancer.Up-regulation of HOXB cluster genes are epigenetically regulated in tamoxifen-resistant MCF7 breast cancer cells
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P2860
HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
HOXB13 mediates tamoxifen resi ...... and inducing IL-6 expression.
@en
HOXB13 mediates tamoxifen resi ...... and inducing IL-6 expression.
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type
label
HOXB13 mediates tamoxifen resi ...... and inducing IL-6 expression.
@en
HOXB13 mediates tamoxifen resi ...... and inducing IL-6 expression.
@nl
prefLabel
HOXB13 mediates tamoxifen resi ...... and inducing IL-6 expression.
@en
HOXB13 mediates tamoxifen resi ...... and inducing IL-6 expression.
@nl
P2093
P2860
P1433
P1476
HOXB13 mediates tamoxifen resi ...... and inducing IL-6 expression.
@en
P2093
Ashley Cimino-Mathews
Chirayu Pankaj Goswami
Christopher Umbricht
Helen Sadik
Howard Y Chang
Kideok Jin
Leigh-Ann Cruz
Leslie Cope
Nilay Shah
Rajnish Gupta
P2860
P304
P356
10.1158/0008-5472.CAN-13-1178
P407
P577
2013-07-05T00:00:00Z