Eradication of human hepatic and pulmonary melanoma metastases in SCID mice by antibody-interleukin 2 fusion proteins.
about
Glycosylation of glycolipids in cancer: basis for development of novel therapeutic approachesTwo new trifunctional antibodies for the therapy of human malignant melanomaPhase I clinical trial of the immunocytokine EMD 273063 in melanoma patients.Guidelines for the welfare and use of animals in cancer research.Ab-IL2 fusion proteins mediate NK cell immune synapse formation by polarizing CD25 to the target cell-effector cell interface.Melanoma immunotherapy by targeted IL-2 depends on CD4(+) T-cell help mediated by CD40/CD40L interaction.Spontaneous nonthymic tumors in SCID mice.Antibody-cytokine fusion proteins for treatment of cancer: engineering cytokines for improved efficacy and safety.Tumor-targeted IL-2 amplifies T cell-mediated immune response induced by gene therapy with single-chain IL-12.Activation of preexisting T cell clones by targeted interleukin 2 therapy.Modified cytokeratins expressed on the surface of carcinoma cells undergo endocytosis upon binding of human monoclonal antibody and its recombinant Fab fragment.In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments.Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma.An antibody-interleukin 2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response.Different tissue distribution properties for glycosylation variants of fusion proteins containing the p40 subunit of murine interleukin-12.Anti-GD2 antibody therapy for GD2-expressing tumors.Immunocytokines: a review of molecules in clinical development for cancer therapy.Breast cancer gene therapy using an adenovirus encoding human IL-2 under control of mammaglobin promoter/enhancer sequences.Delivering safer immunotherapies for cancer.A phase I/IB trial of murine monoclonal anti-GD2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma: a report of the Children's Cancer Group.Human Antibody Fusion Proteins/Antibody Drug Conjugates in Breast and Ovarian CancerCytokines and cancer.Structural and functional insights into the anti-BACE1 Fab fragment that recognizes the BACE1 exosite.Novel antibody-cytokine fusion proteins featuring granulocyte-colony stimulating factor, interleukin-3 and interleukin-4 as payloads.
P2860
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P2860
Eradication of human hepatic and pulmonary melanoma metastases in SCID mice by antibody-interleukin 2 fusion proteins.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Eradication of human hepatic a ...... interleukin 2 fusion proteins.
@en
Eradication of human hepatic a ...... interleukin 2 fusion proteins.
@nl
type
label
Eradication of human hepatic a ...... interleukin 2 fusion proteins.
@en
Eradication of human hepatic a ...... interleukin 2 fusion proteins.
@nl
prefLabel
Eradication of human hepatic a ...... interleukin 2 fusion proteins.
@en
Eradication of human hepatic a ...... interleukin 2 fusion proteins.
@nl
P2093
P2860
P356
P1476
Eradication of human hepatic a ...... interleukin 2 fusion proteins.
@en
P2093
Gillies SD
Mendelsohn J
Pancook JD
Reisfeld RA
P2860
P304
P356
10.1073/PNAS.93.7.2702
P407
P577
1996-04-01T00:00:00Z