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Pre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized miceHumanized mice: novel model for studying mechanisms of human immune-based therapiesNew generation humanized mice for virus research: comparative aspects and future prospectsNovel exosome-targeted T-cell-based vaccine counteracts T-cell anergy and converts CTL exhaustion in chronic infection via CD40L signaling through the mTORC1 pathwayBone marrow transplantation concurrently reconstitutes donor liver and immune system across host species barrier in miceAn infectious murine model for studying the systemic effects of opioids on early HIV pathogenesis in the gutPlasmacytoid dendritic cells promote HIV-1-induced group 3 innate lymphoid cell depletion.The tragic fate of group 3 innate lymphoid cells during HIV-1 infection.The HIV-1 transgenic rat model of neuroHIV.Characterization of neuropathology in the HIV-1 transgenic rat at different ages.Efficient genetic manipulation of the NOD-Rag1-/-IL2RgammaC-null mouse by combining in vitro fertilization and CRISPR/Cas9 technology.Animal models for microbicide safety and efficacy testing.Mice engrafted with human fetal thymic tissue and hematopoietic stem cells develop pathology resembling chronic graft-versus-host disease.HIV-specific CD8⁺ T-cell immunity in humanized bone marrow-liver-thymus miceAn HBV-tolerant immunocompetent model that effectively simulates chronic hepatitis B virus infection in mice.Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs.Liver immune-pathogenesis and therapy of human liver tropic virus infection in humanized mouse models.Latest animal models for anti-HIV drug discovery.Type I interferons suppress viral replication but contribute to T cell depletion and dysfunction during chronic HIV-1 infection.Mice engrafted with human hematopoietic stem cells support a human myeloid cell inflammatory response in vivo.Humanized mouse as an appropriate model for accelerated global HIV research and vaccine development: current trend.Regulatory T Cells Contribute to HIV-1 Reservoir Persistence in CD4+ T Cells Through Cyclic Adenosine Monophosphate-Dependent Mechanisms in Humanized Mice In Vivo.Humanized Mice Engrafted With Human HSC Only or HSC and Thymus Support Comparable HIV-1 Replication, Immunopathology, and Responses to ART and Immune Therapy.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 April 2012
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
HIV-1 immunopathogenesis in humanized mouse models.
@en
HIV-1 immunopathogenesis in humanized mouse models.
@nl
type
label
HIV-1 immunopathogenesis in humanized mouse models.
@en
HIV-1 immunopathogenesis in humanized mouse models.
@nl
prefLabel
HIV-1 immunopathogenesis in humanized mouse models.
@en
HIV-1 immunopathogenesis in humanized mouse models.
@nl
P2860
P356
P1476
HIV-1 immunopathogenesis in humanized mouse models.
@en
P2093
Liguo Zhang
P2860
P2888
P304
P356
10.1038/CMI.2012.7
P577
2012-04-16T00:00:00Z