Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene
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Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanismAltered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrestDown-regulation of a calmodulin-related gene during transformation of human mammary epithelial cellsKeratins as markers that distinguish normal and tumor-derived mammary epithelial cellsExpression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene productPurification and characterization of a newly identified growth factor specific for epithelial cellsChromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cellsInduction of senescence-like phenotypes by forced expression of hic-5, which encodes a novel LIM motif protein, in immortalized human fibroblastsIdentification and partial characterization of a novel membrane-associated protein (MAP17) up-regulated in human carcinomas and modulating cell replication and tumor growthMammary epithelial cell transformation: insights from cell culture and mouse models.Epigenetic changes during cell transformationDisruptive chemicals, senescence and immortalityTime-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modulesMatriptase autoactivation is tightly regulated by the cellular chemical environmentsMullerian inhibiting substance regulates NFkappaB signaling and growth of mammary epithelial cells in vivoSMARCE1 regulates metastatic potential of breast cancer cells through the HIF1A/PTK2 pathwayBuilding risk-on-a-chip models to improve breast cancer risk assessment and prevention.Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cells.Cancer risk related to mammary gland structure and development.Regulation of the activity of matriptase on epithelial cell surfaces by a blood-derived factor.Differential expression of human ferritin H chain gene in immortal human breast epithelial MCF-10F cells.Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells.Isolation of a lactoferrin cDNA clone and its expression in human breast cancer.Characterization of human tracheal epithelial cells transformed by an origin-defective simian virus 40.Modeling platinum sensitive and resistant high-grade serous ovarian cancer: development and applications of experimental systems.Novel isolation and biochemical characterization of immortalized fibroblasts for tissue engineering vocal fold lamina propria.Multi-Color Spectral Transcript Analysis (SPECTRA) for Phenotypic Characterization of Tumor Cells.Phenolic fraction of tobacco smoke condensate potentiates benzo[a]pyerene diol epoxide-induced cell transformation: role of protein kinase C.Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype.Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormonesAn extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cellsTelomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiateThe importance of the microenvironment in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay.Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancerPrimary cilia are decreased in breast cancer: analysis of a collection of human breast cancer cell lines and tissuesDiverse mechanisms of Wnt activation and effects of pathway inhibition on proliferation of human gastric carcinoma cells.An in vitro model of human breast carcinogenesis: epigenetic aspects.Overexpression of c-Myc alters G(1)/S arrest following ionizing radiationABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth
P2860
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P2860
Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Induction of transformation an ...... ter exposure to benzo[a]pyrene
@en
Induction of transformation an ...... er exposure to benzo[a]pyrene.
@nl
type
label
Induction of transformation an ...... ter exposure to benzo[a]pyrene
@en
Induction of transformation an ...... er exposure to benzo[a]pyrene.
@nl
prefLabel
Induction of transformation an ...... ter exposure to benzo[a]pyrene
@en
Induction of transformation an ...... er exposure to benzo[a]pyrene.
@nl
P2860
P356
P1476
Induction of transformation an ...... ter exposure to benzo[a]pyrene
@en
P2093
J C Bartley
M R Stampfer
P2860
P304
P356
10.1073/PNAS.82.8.2394
P407
P577
1985-04-01T00:00:00Z