Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritis. - Wikidata - wikimedia - TriplyDB

Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritis.

Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritis.

http://www.wikidata.org/entity/Q37690364

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The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis.Progranulin-derived Atsttrin directly binds to TNFRSF25 (DR3) and inhibits TNF-like ligand 1A (TL1A) activity.Progranulin facilitates conversion and function of regulatory T cells under inflammatory conditions.Three TNFR-binding domains of PGRN act independently in inhibition of TNF-alpha binding and activity.Intra-articular transplantation of atsttrin-transduced mesenchymal stem cells ameliorate osteoarthritis development.Progranulin suppresses titanium particle induced inflammatory osteolysis by targeting TNFα signaling.Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease.New discovery rarely runs smooth: an update on progranulin/TNFR interactions Progranulin: A key player in autoimmune diseases.Review: Novel Insights Into Tumor Necrosis Factor Receptor, Death Receptor 3, and Progranulin Pathways in Arthritis and Bone Remodeling.The role of progranulin in arthritis.Progranulin protects against osteoarthritis through interacting with TNF-α and β-Catenin signalling.Serum progranulin levels in Hispanic rheumatoid arthritis patients treated with TNF antagonists: a prospective, observational study.Proinflammatory progranulin antibodies in inflammatory bowel diseases.Intranasal administration of recombinant progranulin inhibits bronchial smooth muscle hyperresponsiveness in mouse allergic asthma.Association of polymorphisms in TNF and GRN genes with ankylosing spondylitis in a Chinese Han population.Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease.

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Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritis.

http://www.wikidata.org/entity/Q37690364

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article científic

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scientific article published on January 2013

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vedecký článok

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Progranulin antibodies enterta ...... ents with psoriatic arthritis.

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Progranulin antibodies enterta ...... ents with psoriatic arthritis.

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Progranulin antibodies enterta ...... ents with psoriatic arthritis.

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Progranulin antibodies enterta ...... ents with psoriatic arthritis.

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Progranulin antibodies enterta ...... ents with psoriatic arthritis.

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Arthritis Research and Therapy

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Progranulin antibodies enterta ...... ents with psoriatic arthritis.

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Evi Regitz

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Gunter Assmann

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Klaus-Dieter Preuss

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Lorenz Thurner

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Marina Zaks

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Mei Fang Ong

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Natalie Fadle

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P2860

Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domains

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin.

Immunohistochemical markers for arthritis in psoriasis.

Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).

Progranulin antibodies in autoimmune diseases.

The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice.

Infliximab improves signs and symptoms of psoriatic arthritis: results of the IMPACT 2 trial.

Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein shedding

Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells.

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