Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease. - Wikidata - wikimedia - TriplyDB

Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease.

Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease.

http://www.wikidata.org/entity/Q37691070

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The relevance of beta-amyloid on markers of Alzheimer's disease in clinically normal individuals and factors that influence these associations Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease.Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition.APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice.Age, Sex, and APOE ε4 Effects on Memory, Brain Structure, and β-Amyloid Across the Adult Life Span.Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimer's disease pathogenesis.Interaction between years of education and APOE ε4 status on frontal and temporal metabolism.APOE-ε4 selectively modulates posteromedial cortex activity during scene perception and short-term memory in young healthy adults.APOE-by-sex interactions on brain structure and metabolism in healthy elderly controls.Beta-amyloid and cognitive decline in late middle age: Findings from the Wisconsin Registry for Alzheimer's Prevention study.Serum Hepcidin Levels, Iron Dyshomeostasis and Cognitive Loss in Alzheimer's Disease.Alzheimer's disease genetics: from the bench to the clinic.Polygenic risk of Alzheimer disease is associated with early- and late-life processes.Visual system manifestations of Alzheimer's disease.Multimodal characterization of older APOE2 carriers reveals selective reduction of amyloid load.Altered Energy Metabolism Pathways in the Posterior Cingulate in Young Adult Apolipoprotein E ɛ4 Carriers.Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer's disease-like pathology.The Endosomal-Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo.Complexity and Selectivity of γ-Secretase Cleavage on Multiple Substrates: Consequences in Alzheimer's Disease and Cancer.APOE genotype and early β-amyloid accumulation in older adults without dementia.The Relationship of Brain Amyloid Load and APOE Status to Regional Cortical Thinning and Cognition in the ADNI Cohort.Metabolic brain networks in aging and preclinical Alzheimer's disease.

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Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease.

http://www.wikidata.org/entity/Q37691070

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 03 September 2013

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

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name

Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease.

@en

Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease.

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type

label

Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease.

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Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease.

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prefLabel

Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease.

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Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease.

@nl

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Alzheimers Research & Therapy

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Apolipoprotein E as a β-amyloid-independent factor in Alzheimer's disease

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Andrew B Wolf

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Eric M Reiman

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Guojun Bu

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Jon Valla

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Richard J Caselli

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P2860

Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease

Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling

Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease

Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease

Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Apolipoprotein E: far more than a lipid transport protein

Apolipoprotein-mediated pathways of lipid antigen presentation

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10.1186/ALZRT204

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Alzheimer's disease

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3979087

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