Inherent instability of the retinitis pigmentosa P23H mutant opsin.

Inherent instability of the retinitis pigmentosa P23H mutant opsin.

Item
http://www.wikidata.org/entity/Q37691592
Biology and therapy of inherited retinal degenerative disease: insights from mouse modelsExclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa.A High-Throughput Drug Screening Strategy for Detecting Rhodopsin P23H Mutant Rescue and Degradation.Disruption of Rhodopsin Dimerization with Synthetic Peptides Targeting an Interaction InterfaceRescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration.Targeting the Proteostasis Network in Rhodopsin Retinitis Pigmentosa.A missense mutation in Grm6 reduces but does not eliminate mGluR6 expression or rod depolarizing bipolar cell function.Structural and molecular bases of rod photoreceptor morphogenesis and disease.High-throughput screening assays to identify small molecules preventing photoreceptor degeneration caused by the rhodopsin P23H mutation.Transcriptome profiling of NIH3T3 cell lines expressing opsin and the P23H opsin mutant identifies candidate drugs for the treatment of retinitis pigmentosa.The molecular and cellular basis of rhodopsin retinitis pigmentosa reveals potential strategies for therapy.A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.
P2860

Inherent instability of the retinitis pigmentosa P23H mutant opsin.

Item
http://www.wikidata.org/entity/Q37691592
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 February 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Inherent instability of the retinitis pigmentosa P23H mutant opsin.
@en
Inherent instability of the retinitis pigmentosa P23H mutant opsin.
@nl
type
label
Inherent instability of the retinitis pigmentosa P23H mutant opsin.
@en
Inherent instability of the retinitis pigmentosa P23H mutant opsin.
@nl
prefLabel
Inherent instability of the retinitis pigmentosa P23H mutant opsin.
@en
Inherent instability of the retinitis pigmentosa P23H mutant opsin.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Inherent instability of the retinitis pigmentosa P23H mutant opsin.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932