MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL.

MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL.

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http://www.wikidata.org/entity/Q37692596
Targeting CDK6 in cancer: State of the art and new insightsCDK6 as a key regulator of hematopoietic and leukemic stem cell activationThe molecular mechanics of mixed lineage leukemia.Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.Targeting cell cycle regulators in hematologic malignancies.Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6.MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.Therapeutic targeting the cell division cycle 25 (CDC25) phosphatases in human acute myeloid leukemia--the possibility to target several kinases through inhibition of the various CDC25 isoforms.Emerging therapeutic targets for the treatment of human acute myeloid leukemia (part 1) - gene transcription, cell cycle regulation, metabolism and intercellular communication.CDK6-a review of the past and a glimpse into the future: from cell-cycle control to transcriptional regulation.TBP loading by AF4 through SL1 is the major rate-limiting step in MLL fusion-dependent transcription.H19 derived microRNA-675 regulates cell proliferation and migration through CDK6 in glioma.Quantitative proteomic analysis of EZH2 inhibition in acute myeloid leukemia reveals the targets and pathways that precede the induction of cell death.Targeting CDK6 and BCL2 exploits the "MYB addiction" of Ph+ acute lymphoblastic leukemia.
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MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL.

Item
http://www.wikidata.org/entity/Q37692596
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
MLL fusion-driven activation o ...... in MLL-rearranged infant ALL.
@en
MLL fusion-driven activation o ...... in MLL-rearranged infant ALL.
@nl
type
label
MLL fusion-driven activation o ...... in MLL-rearranged infant ALL.
@en
MLL fusion-driven activation o ...... in MLL-rearranged infant ALL.
@nl
prefLabel
MLL fusion-driven activation o ...... in MLL-rearranged infant ALL.
@en
MLL fusion-driven activation o ...... in MLL-rearranged infant ALL.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
MLL fusion-driven activation o ...... in MLL-rearranged infant ALL.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932