Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue.
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Imputation and subset based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33DNA methylation changes in epithelial ovarian cancer histotypes.Deciphering associations for lung cancer risk through imputation and analysis of 12,316 cases and 16,831 controlsRelation between Established Glioma Risk Variants and DNA Methylation in the TumorWinner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level DataGenetic variation at 16q24.2 is associated with small vessel stroke.Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers.A Flexible, Efficient Binomial Mixed Model for Identifying Differential DNA Methylation in Bisulfite Sequencing Data.Integrative Analysis of Multi-omics Data for Discovery and Functional Studies of Complex Human Diseases.Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis.The Influences of Genetic and Environmental Factors on Methylome-wide Association Studies for Human Diseases.CDH13 promoter SNPs with pleiotropic effect on cardiometabolic parameters represent methylation QTLs.Path from schizophrenia genomics to biology: gene regulation and perturbation in neurons derived from induced pluripotent stem cells and genome editing.Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent lociA pooling-based approach to mapping genetic variants associated with DNA methylation.Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers.DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain TumorsSomatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study.Methylation quantitative trait locus analysis of osteoarthritis links epigenetics with genetic riskHigh density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fractionThe effect of 5-fluorouracil/leucovorin chemotherapy on CpG methylation, or the confounding role of leukocyte heterogeneity: An illustrationSystematic identification of genetic influences on methylation across the human life course.Genetic and environmental influences interact with age and sex in shaping the human methylome.Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA MethylationLeveraging gene-environment interactions and endotypes for asthma gene discovery.The importance of detailed epigenomic profiling of different cell types within organs.The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.Collapsed methylation quantitative trait loci analysis for low frequency and rare variants.Mendelian randomization: applications and limitations in epigenetic studies.Quantitative assessment of the diagnostic role of FHIT promoter methylation in non-small cell lung cancerEpigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers.Population and allelic variation of A-to-I RNA editing in human transcriptomes.Role of ATG10 expression quantitative trait loci in non-small cell lung cancer survival.HAPRAP: a haplotype-based iterative method for statistical fine mapping using GWAS summary statisticsGenetic variation in one-carbon metabolism in relation to genome-wide DNA methylation in breast tissue from heathy women.Epigenetic silencing of downstream genes mediated by tandem orientation in lung cancer.DNA methylation profiling in human lung tissue identifies genes associated with COPD.Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder.Exhaustive search for epistatic effects on the human methylome.
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Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 February 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Characterizing the genetic bas ...... ally normal human lung tissue.
@en
Characterizing the genetic bas ...... ally normal human lung tissue.
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type
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Characterizing the genetic bas ...... ally normal human lung tissue.
@en
Characterizing the genetic bas ...... ally normal human lung tissue.
@nl
prefLabel
Characterizing the genetic bas ...... ally normal human lung tissue.
@en
Characterizing the genetic bas ...... ally normal human lung tissue.
@nl
P2093
P2860
P50
P356
P1476
Characterizing the genetic bas ...... ally normal human lung tissue.
@en
P2093
Andrew Warner
Beiyun Zhou
Brian S I Chung
Diane S Lee
Ite A Laird-Offringa
Jianxin Shi
Jubao Duan
Kimberly D Siegmund
Margaret A Tucker
Maria Teresa Landi
P2860
P2888
P356
10.1038/NCOMMS4365
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P50
P577
2014-02-27T00:00:00Z