Mismatch repair deficient colorectal cancer in the era of personalized treatment.
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MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2)Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1Postreplicative mismatch repair.Biomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and othersRole of Deficient Mismatch Repair in the Personalized Management of Colorectal CancerMRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trialEstablishment, characterization and chemosensitivity of three mismatch repair deficient cell lines from sporadic and inherited colorectal carcinomasBody mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genesPrognostic impact of FoxP3+ regulatory T cells in relation to CD8+ T lymphocyte density in human colon carcinomas.miR-1290 Is a Biomarker in DNA-Mismatch-Repair-Deficient Colon Cancer and Promotes Resistance to 5-Fluorouracil by Directly Targeting hMSH2.Evaluation of guanylyl cyclase C lymph node status for colon cancer staging and prognosis.Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks.Colorectal cancer with liver metastases: neoadjuvant chemotherapy, surgical resection first or palliation alone?Msh6 protects mature B cells from lymphoma by preserving genomic stability.Deep sequencing of the X chromosome reveals the proliferation history of colorectal adenomas.DNA mismatch repair and oxidative DNA damage: implications for cancer biology and treatment.The genomic landscape of oesophagogastric junctional adenocarcinoma.Tumor markers in colorectal cancer, gastric cancer and gastrointestinal stromal cancers: European group on tumor markers 2014 guidelines updateCytosine-based nucleoside analogs are selectively lethal to DNA mismatch repair-deficient tumour cells by enhancing levels of intracellular oxidative stress.MSH3 mediates sensitization of colorectal cancer cells to cisplatin, oxaliplatin, and a poly(ADP-ribose) polymerase inhibitor.Elevated incidence of polyp formation in APC(Min/⁺)Msh2⁻/⁻ mice is independent of nitric oxide-induced DNA mutationsDNA mismatch repair-related protein loss as a prognostic factor in endometrial cancers.An inducible, isogenic cancer cell line system for targeting the state of mismatch repair deficiency.Drug therapy for hereditary cancersEGFR inhibits DNA mismatch repairA survey of tandem repeat instabilities and associated gene expression changes in 35 colorectal cancers.Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancersDNA helicases involved in DNA repair and their roles in cancerOncologic management of hereditary colorectal cancer.Balancing repair and tolerance of DNA damage caused by alkylating agentsPersonalized medicine for targeted and platinum-based chemotherapy of lung and bladder cancer.Heterozygous colon cancer-associated mutations of SAMHD1 have functional significanceGenetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome.Hereditary cancer syndromes: utilizing DNA repair deficiency as therapeutic targetThe role of personalized medicine in metastatic colorectal cancer: an evolving landscape.A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair DeficienciesDNA repair in cancer: emerging targets for personalized therapy.Modulation of miR-21 signaling by MPS1 in human glioblastomaTargeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.Emerging therapeutic targets in endometrial cancer.
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Mismatch repair deficient colorectal cancer in the era of personalized treatment.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 February 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mismatch repair deficient colorectal cancer in the era of personalized treatment.
@en
Mismatch repair deficient colorectal cancer in the era of personalized treatment.
@nl
type
label
Mismatch repair deficient colorectal cancer in the era of personalized treatment.
@en
Mismatch repair deficient colorectal cancer in the era of personalized treatment.
@nl
prefLabel
Mismatch repair deficient colorectal cancer in the era of personalized treatment.
@en
Mismatch repair deficient colorectal cancer in the era of personalized treatment.
@nl
P2860
P50
P1476
Mismatch repair deficient colorectal cancer in the era of personalized treatment.
@en
P2093
Madeleine Hewish
Sarah A Martin
P2860
P304
P356
10.1038/NRCLINONC.2010.18
P407
P577
2010-02-23T00:00:00Z