DISC1 as a therapeutic target for mental illnesses. - Wikidata - wikimedia - TriplyDB

DISC1 as a therapeutic target for mental illnesses.

DISC1 as a therapeutic target for mental illnesses.

http://www.wikidata.org/entity/Q37698116

about

Molecular underpinnings of prefrontal cortex development in rodents provide insights into the etiology of neurodevelopmental disorders cAMP signaling in brain is decreased in unmedicated depressed patients and increased by treatment with a selective serotonin reuptake inhibitor.Modulation of Amyloid β-Protein (Aβ) Assembly by Homologous C-Terminal Fragments as a Strategy for Inhibiting Aβ Toxicity.Association between 5q23.2-located polymorphism of CTXN3 gene (Cortexin 3) and schizophrenia in European-Caucasian males; implications for the aetiology of schizophrenia.Half-life of DISC1 protein and its pathological significance under hypoxia stress Utility and validity of DISC1 mouse models in biological psychiatry.Disrupted in schizophrenia 1 (DISC1) L100P mutants have impaired activity-dependent plasticity in vivo and in vitro.The impact of Disrupted-in-Schizophrenia 1 (DISC1) on the dopaminergic system: a systematic review.The potential of DISC1 protein as a therapeutic target for mental illness.DISC1 causes associative memory and neurodevelopmental defects in fruit flies.Disrupted in schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels.Genetic interaction of DISC1 and Neurexin in the development of fruit fly glutamatergic synapses

P2860

Q26853035-1740965F-E12E-4DF9-B258-EACA4D3B6131 Q33554709-2D3D9BB5-3684-41C4-8C3E-17F54C2E5934 Q33745468-6E2181AB-EECB-433D-B199-BEF2C897BA30 Q35200888-EC800955-CDD2-40F9-AF92-F083781C1EA7 Q35802091-E1D8CC1D-3CE1-4F13-8A0C-61501928CB99 Q36717234-A50E9859-0B5E-4052-BC82-A6A5EBE8957F Q37347839-D2C186CD-0477-4431-9F8B-6C111786C48F Q37633236-C46D0BF9-E4A8-4DF1-99A7-E2B807025952 Q41096648-C0907B2E-78CF-4C4A-81E2-27C124675A77 Q41444596-58CE2F20-3EF1-4B01-A0F4-5303F8866189 Q42027335-C42FFA0F-43D5-42B7-898E-7390B53B8895 Q42611080-83D77154-36BF-4094-80D3-77CB2B0DB63F

P2860

DISC1 as a therapeutic target for mental illnesses.

http://www.wikidata.org/entity/Q37698116

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

DISC1 as a therapeutic target for mental illnesses.

@en

DISC1 as a therapeutic target for mental illnesses.

@nl

type

label

DISC1 as a therapeutic target for mental illnesses.

@en

DISC1 as a therapeutic target for mental illnesses.

@nl

prefLabel

DISC1 as a therapeutic target for mental illnesses.

@en

DISC1 as a therapeutic target for mental illnesses.

@nl

P1433

Q37698116-E4DC0513-AA44-4EAB-97C4-D359C805C08A

P1476

Q37698116-F05B5E8A-5F55-4EAE-8A5E-CCF5A2F771A5

P2093

Q37698116-7532CEDB-7489-480B-8FC9-3DD63C7934A0

Q37698116-93C47DBD-93E6-4C97-9CF1-9EDF4CE9D7A7

P2860

Q37698116-025CADF4-FE35-4BC2-80B7-2C5A8BB026D5

Q37698116-02CEA07D-F947-443D-8FCD-70A3070AB018

Q37698116-04EA04D3-906F-4A59-B160-57C2A63449AD

Q37698116-0DC810A3-1D98-4B0E-A018-A4A4A7480C80

Q37698116-0E47BD4D-0B5E-4354-BAB3-9B75C5E65BF1

Q37698116-11AE8C7C-A0D9-44DF-88DA-1C93ADCCEB30

Q37698116-11B00E6A-C722-4052-9B1D-B8A669CA2410

Q37698116-14BBC70C-140B-4BA3-B2F2-66C207BEF24D

Q37698116-16D9530D-8E1A-4C9B-91AC-53E215380A23

Q37698116-1742B2DE-9B7C-4DE5-AE8F-4072C0CD5E2A

P304

Q37698116-F302C4E2-C27B-45F4-AB1D-B1D30830EE9D

P31

Q37698116-9CE487DB-184E-4B8C-B930-EBEE087C45BB

P356

Q37698116-B1C6522D-D91A-4CA0-BFFE-78DADE76769F

P407

Q37698116-32CD1725-B34F-40BB-830A-CA6FE6EE6854

P433

Q37698116-08CA99F9-E957-4524-8B1E-6FBD16D75981

P478

Q37698116-8F220091-A2C4-4CC4-8005-E19450140764

P50

Q37698116-EA58D2D8-DDBA-4210-B946-C32746061551

P577

Q37698116-19BAE700-56B8-4BA4-A039-093EB9782280

P698

Q37698116-BE24FF57-A3DD-4BA6-AF9A-594EF5872393

P932

Q37698116-0939BC4C-D5ED-45F1-A06C-5BB4BCA20A78

P356

14728222.2012.719879

P1433

Expert Opinion on Therapeutic Targets

P1476

DISC1 as a therapeutic target for mental illnesses

@en

P2093

Akira Sawa

http://www.w3.org/2001/XMLSchema#string

Nao J Gamo

http://www.w3.org/2001/XMLSchema#string

P2860

GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS

DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation

DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

Deletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesis

Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1

Dynamic Network Connectivity: A new form of neuroplasticity

P304

1151-1160

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1517/14728222.2012.719879

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

16

http://www.w3.org/2001/XMLSchema#string

P50

Takatoshi Hikida

P577

2012-11-06T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23130881

http://www.w3.org/2001/XMLSchema#string

P932

3983783

http://www.w3.org/2001/XMLSchema#string