α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction.
about
Mechanobiology of myofibroblast adhesion in fibrotic cardiac diseaseVASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin moduleForce dependent biotinylation of myosin IIA by α-catenin tagged with a promiscuous biotin ligaseSynaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturationControl of cell-cell forces and collective cell dynamics by the intercellular adhesome.New functions for alpha-catenins in health and disease: from cancer to heart regenerationAllosteric Regulation of E-Cadherin Adhesion.E-cadherin-mediated force transduction signals regulate global cell mechanicsLocal VE-cadherin mechanotransduction triggers long-ranged remodeling of endothelial monolayers.Formation of adherens junctions leads to the emergence of a tissue-level tension in epithelial monolayers.Vinculin in cell-cell and cell-matrix adhesions.Switching of α-Catenin From Epithelial to Neuronal Type During Lens Epithelial Cell Differentiation.α-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism.Structural Determinants of the Mechanical Stability of α-Catenin.Spatial distribution of cell-cell and cell-ECM adhesions regulates force balance while main-taining E-cadherin molecular tension in cell pairs.The mechanotransduction machinery at work at adherens junctions.Actomyosin-generated tension on cadherin is similar between dividing and non-dividing epithelial cells in early Xenopus laevis embryos.There are four dynamically and functionally distinct populations of E-cadherin in cell junctions.Using magnets and magnetic beads to dissect signaling pathways activated by mechanical tension applied to cellsαT-Catenin Is a Constitutive Actin-binding α-Catenin That Directly Couples the Cadherin·Catenin Complex to Actin FilamentsTension-sensitive actin assembly supports contractility at the epithelial zonula adherens.Stiff Substrates Increase Inflammation-Induced Endothelial Monolayer Tension and Permeability.Contraction and elongation: Mechanics underlying cell boundary deformations in epithelial tissue.Intracellular Domain Contacts Contribute to Ecadherin Constitutive Dimerization in the Plasma Membrane.A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion.Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread.Deletion of the cytoplasmic domain of N-cadherin reduces, but does not eliminate, traction force-transmission.Biochemical analysis of force-sensitive responses using a large-scale cell stretch device.Intermediate Filaments and the Plasma Membrane.Actin-Based Adhesion Modules Mediate Cell Interactions with the Extracellular Matrix and Neighboring Cells.E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shapeBiophysical Tools to Study Cellular Mechanotransduction.Dynamic visualization of α-catenin reveals rapid, reversible conformation switching between tension states.Cell adhesion. The minimal cadherin-catenin complex binds to actin filaments under force.Linking E-cadherin mechanotransduction to cell metabolism through force-mediated activation of AMPK.E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning.Salt bridges gate α-catenin activation at intercellular junctions.Mechanobiology of collective cell behaviours.Receptor-mediated cell mechanosensing.Epithelial Organization: The Gut and Beyond.
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α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 February 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction.
@en
α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction.
@nl
type
label
α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction.
@en
α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction.
@nl
prefLabel
α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction.
@en
α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction.
@nl
P2093
P2860
P50
P356
P1476
α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction.
@en
P2093
Adrienne K Barry
Deborah E Leckband
Hamid Tabdili
Ismaeel Muhamed
Nitesh Shashikanth
P2860
P304
P356
10.1242/JCS.139014
P407
P577
2014-02-12T00:00:00Z