Improving genetic risk prediction by leveraging pleiotropy.
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Application of computational methods in genetic study of inflammatory bowel diseaseImplications of pleiotropy: challenges and opportunities for mining Big Data in biomedicineCollective effects of common SNPs in foraging decisions in Caenorhabditis elegans and an integrative method of identification of candidate genes.Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer TypesDeveloping and evaluating polygenic risk prediction models for stratified disease prevention.Post-GWAS Prioritization Through Data Integration Provides Novel Insights on Chronic Obstructive Pulmonary Disease.Prediction of gene expression with cis-SNPs using mixed models and regularization methodsLeveraging functional annotations in genetic risk prediction for human complex diseases.Joint modeling of genetically correlated diseases and functional annotations increases accuracy of polygenic risk predictionIdentifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk FactorsJoint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder.GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotationMachine learning derived risk prediction of anorexia nervosaPervasive pleiotropy between psychiatric disorders and immune disorders revealed by integrative analysis of multiple GWAS.graph-GPA: A graphical model for prioritizing GWAS results and investigating pleiotropic architecture.Leveraging electronic health records to study pleiotropic effects on bipolar disorder and medical comorbidities.Leveraging Multi-ethnic Evidence for Risk Assessment of Quantitative Traits in Minority Populations.Polygenic scores via penalized regression on summary statistics.An Analytic Solution to the Computation of Power and Sample Size for Genetic Association Studies under a Pleiotropic Mode of Inheritance.Integrative genetic risk prediction using non-parametric empirical Bayes classification.An Adaptive Association Test for Multiple Phenotypes with GWAS Summary Statistics.Accumulation of minor alleles and risk prediction in schizophreniaLLR: A latent low-rank approach to colocalizing genetic risk variants in multiple GWAS.The ubiquity of pleiotropy in human disease.Identification of pleiotropic genetic variants affecting osteoporosis risk in a Korean elderly cohort.Testing Genetic Pleiotropy with GWAS Summary Statistics for Marginal and Conditional Analyses.Improving genetic prediction by leveraging genetic correlations among human diseases and traits.
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Improving genetic risk prediction by leveraging pleiotropy.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 13 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Improving genetic risk prediction by leveraging pleiotropy.
@en
Improving genetic risk prediction by leveraging pleiotropy.
@nl
type
label
Improving genetic risk prediction by leveraging pleiotropy.
@en
Improving genetic risk prediction by leveraging pleiotropy.
@nl
prefLabel
Improving genetic risk prediction by leveraging pleiotropy.
@en
Improving genetic risk prediction by leveraging pleiotropy.
@nl
P2093
P2860
P1433
P1476
Improving genetic risk prediction by leveraging pleiotropy.
@en
P2093
P2860
P2888
P304
P356
10.1007/S00439-013-1401-5
P577
2013-12-13T00:00:00Z