Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival.
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Recapitulating the Tumor Ecosystem Along the Metastatic Cascade Using 3D Culture ModelsGene expression profiling of whole blood cells supports a more efficient mitochondrial respiration in hypoxia-challenged gilthead sea bream (Sparus aurata)Polymorphic regulation of mitochondrial fission and fusion modifies phenotypes of microglia in neuroinflammation.Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effectSimultaneous Hypoxia and Low Extracellular pH Suppress Overall Metabolic Rate and Protein Synthesis In VitroExtracellular pH Modulates Neuroendocrine Prostate Cancer Cell Metabolism and Susceptibility to the Mitochondrial Inhibitor Niclosamide.A novel algorithm identifies stress-induced alterations in mitochondrial connectivity and inner membrane structure from confocal images.1α,25-Dihydroxyvitamin D3 Regulates Mitochondrial Oxygen Consumption and Dynamics in Human Skeletal Muscle CellsRequirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.PARK2-dependent mitophagy induced by acidic postconditioning protects against focal cerebral ischemia and extends the reperfusion window.Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis.Blood-brain barrier-supported neurogenesis in healthy and diseased brain.Diluted serum from calorie-restricted animals promotes mitochondrial β-cell adaptations and protect against glucolipotoxicity.Permissive role of cytosolic pH acidification in neurodegeneration: A closer look at its causes and consequences.Mitochondrial dynamics in neuronal injury, development and plasticity.Mitochondrial dynamics in the regulation of neurogenesis: From development to the adult brain.Mitochondrial stress controls the radiosensitivity of the oxygen effect: Implications for radiotherapy.Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cellsNeuroprotection and acidosis induced by cortical spreading depression.Whole-Brain N-Acetylaspartate Concentration Is Preserved during Mild Hypercapnia Challenge.Protein kinase D activation induces mitochondrial fragmentation and dysfunction in cardiomyocytes.Pluripotency transcription factors and Metabolic reprogramming of mitochondria in tumor-initiating stem-like cells.Tumour acidosis: from the passenger to the driver's seat.Acidotoxicity via ASIC1a Mediates Cell Death during Oxygen Glucose Deprivation and Abolishes Excitotoxicity.Metabolic Barriers to T Cell Function in Tumors.A Brake for B Cell Proliferation: Appropriate responses to metabolic stress are crucial to maintain B cell viability and prevent malignant outgrowth.
P2860
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P2860
Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on April 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Acidosis overrides oxygen depr ...... al function and cell survival.
@en
Acidosis overrides oxygen depr ...... al function and cell survival.
@nl
type
label
Acidosis overrides oxygen depr ...... al function and cell survival.
@en
Acidosis overrides oxygen depr ...... al function and cell survival.
@nl
prefLabel
Acidosis overrides oxygen depr ...... al function and cell survival.
@en
Acidosis overrides oxygen depr ...... al function and cell survival.
@nl
P2093
P2860
P50
P356
P1476
Acidosis overrides oxygen depr ...... ial function and cell survival
@en
P2093
David Patten
Jason G MacLaurin
Jennifer Guadagno
Michelle Tarabay
Mireille Khacho
Pamela Khacho
Ruth S Slack
Sean P Cregan
P2860
P2888
P356
10.1038/NCOMMS4550
P407
P577
2014-04-01T00:00:00Z