Targeting DOT1L action and interactions in leukemia: the role of DOT1L in transformation and development.
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Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectivesTargets, models and challenges in osteoarthritis researchGenome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritisA medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L.Histone H3K79 methyltransferase Dot1L is directly activated by thyroid hormone receptor during Xenopus metamorphosis.Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.Histone methyltransferase Dot1L plays a role in postembryonic development in Xenopus tropicalis.The histone methyltransferase DOT1L: regulatory functions and a cancer therapy target.Dot1l expression predicts adverse postoperative prognosis of patients with clear-cell renal cell carcinoma.A modified epigenetics toolbox to study histone modifications on the nucleosome core.The heterogeneity of pediatric MLL-rearranged acute myeloid leukemia.Histone methylation in myelodysplastic syndromes.A genome wide transcriptional model of the complex response to pre-TCR signalling during thymocyte differentiation.Bat3 facilitates H3K79 dimethylation by DOT1L and promotes DNA damage-induced 53BP1 foci at G1/G2 cell-cycle phases.Histone methyltransferase Dot1L is a coactivator for thyroid hormone receptor during Xenopus development.
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Targeting DOT1L action and interactions in leukemia: the role of DOT1L in transformation and development.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2010
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Targeting DOT1L action and int ...... ransformation and development.
@en
Targeting DOT1L action and int ...... ransformation and development.
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type
label
Targeting DOT1L action and int ...... ransformation and development.
@en
Targeting DOT1L action and int ...... ransformation and development.
@nl
prefLabel
Targeting DOT1L action and int ...... ransformation and development.
@en
Targeting DOT1L action and int ...... ransformation and development.
@nl
P2093
P2860
P1476
Targeting DOT1L action and int ...... ransformation and development.
@en
P2093
Evan R Barry
Gareth N Corry
Theodore P Rasmussen
P2860
P304
P356
10.1517/14728221003623241
P407
P577
2010-04-01T00:00:00Z