Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage.
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Homodimerization and hetero-oligomerization of the single-domain trefoil protein pNR-2/pS2 through cysteine 58Intestinal trefoil factor binds to intestinal epithelial cells and induces nitric oxide production: priming and enhancing effects of mucinMucins and inflammatory bowel diseaseThe human trefoil peptide, TFF1, is present in different molecular forms that are intimately associated with mucus in normal stomachBovine colostrum is a health food supplement which prevents NSAID induced gut damageHeterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor 1Growth factors in inflammatory bowel disease.Trefoil peptides and surgical disease.Intestinal growth factors: potential use in the treatment of inflammatory bowel disease and their role in mucosal healing.X. Trefoil peptide and EGF receptor/ligand transgenic mice.A paradoxical reduction in susceptibility to colonic injury upon targeted transgenic ablation of goblet cellsNOD-like receptors in intestinal homeostasis and epithelial tissue repair.TFF1 activates p53 through down-regulation of miR-504 in gastric cancerTrefoil peptides in airway epithelium: an important addition to the plethora of peptides.A variant form of the human deleted in malignant brain tumor 1 (DMBT1) gene shows increased expression in inflammatory bowel diseases and interacts with dimeric trefoil factor 3 (TFF3).The effects of keratinocyte growth factor in preclinical models of mucositis.Trefoil factor 1 acts to suppress senescence induced by oncogene activation during the cellular transformation processSalmonella Interaction with and Passage through the Intestinal Mucosa: Through the Lens of the OrganismDeficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice.Distribution and metabolism of intravenously administered trefoil factor 2/porcine spasmolytic polypeptide in the rat.Metabolism of oral trefoil factor 2 (TFF2) and the effect of oral and parenteral TFF2 on gastric and duodenal ulcer healing in the rat.Mucin gene expression in Barrett's oesophagus: an in situ hybridisation and immunohistochemical study.Infections in patients with inherited defects in phagocytic function.Trefoil factor 1 is required for the commitment programme of mouse oxyntic epithelial progenitors.Zinc carnosine, a health food supplement that stabilises small bowel integrity and stimulates gut repair processes.The trefoil factor 1 participates in gastrointestinal cell differentiation by delaying G1-S phase transition and reducing apoptosis.Modulation of gut-associated lymphoid tissue functions with genetically modified Lactococcus lactis.Mouse models for gastric cancer: Matching models to biological questions.Trefoil factor family peptides--friends or foes?Trefoil Factor Peptides and Gastrointestinal Function.Up-regulation of pS2 expression during the development of adenocarcinomas but not squamous cell carcinomas of the uterine cervix, independently of expression of c-jun or oestrogen and progesterone receptors.The trefoil peptide TFF1 inhibits the growth of the human gastric adenocarcinoma cell line AGS.Osmotic changes and ethanol modify TFF gene expression in gastrointestinal cell lines.Targeting Hypoxia to Augment Mucosal Barrier FunctionCirculating levels of glucagon-like peptide-2 in human subjects with inflammatory bowel disease.Trefoil factor 2 negatively regulates type 1 immunity against Toxoplasma gondii.The trefoil factor interacting protein TFIZ1 binds the trefoil protein TFF1 preferentially in normal gastric mucosal cells but the co-expression of these proteins is deregulated in gastric cancer.Modulation of epithelial cell adhesion in gastrointestinal homeostasis.Tumour necrosis factor alpha and nuclear factor kappaB inhibit transcription of human TFF3 encoding a gastrointestinal healing peptide.Interaction of trefoil family factors with mucins: clues to their mechanism of action?
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P2860
Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on March 1996
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Transgenic mice that overexpre ...... sistance to intestinal damage.
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Transgenic mice that overexpre ...... sistance to intestinal damage.
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type
label
Transgenic mice that overexpre ...... sistance to intestinal damage.
@en
Transgenic mice that overexpre ...... sistance to intestinal damage.
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Transgenic mice that overexpre ...... sistance to intestinal damage.
@en
Transgenic mice that overexpre ...... sistance to intestinal damage.
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P2093
P2860
P356
P1476
Transgenic mice that overexpre ...... esistance to intestinal damage
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P2093
R A Chinery
R J Playford
T Marchbank
P2860
P304
P356
10.1073/PNAS.93.5.2137
P407
P577
1996-03-01T00:00:00Z