A heterotrimeric G protein complex couples the muscarinic m1 receptor to phospholipase C-beta.
about
Cloning, expression and subcellular localization of two novel splice variants of mouse transient receptor potential channel 2Galpha(14) links a variety of G(i)- and G(s)-coupled receptors to the stimulation of phospholipase CG protein heterotrimer Galpha13beta1gamma3 couples the angiotensin AT1A receptor to increases in cytoplasmic Ca2+ in rat portal vein myocytesSarcoplasmic/endoplasmic-reticulum-Ca2+-ATPase-mediated Ca2+ reuptake, and not Ins(1,4,5)P3 receptor inactivation, prevents the activation of macroscopic Ca2+ release-activated Ca2+ current in the presence of physiological Ca2+ buffer in rat basophiPhospholipase C isozymes selectively couple to specific neurotransmitter receptorsThe G protein beta subunit is a determinant in the coupling of Gs to the beta 1-adrenergic and A2a adenosine receptors.The G protein beta5 subunit interacts selectively with the Gq alpha subunit.Crosstalk between Galpha(i)- and Galpha(q)-coupled receptors is mediated by Gbetagamma exchange.G protein-coupled receptor/arrestin3 modulation of the endocytic machineryDifferential localization of G protein βγ subunits.Cell cycle-dependent coupling of the vasopressin V1a receptor to different G proteins.Galpha14 and Galphaq mediate the response to trypsin in Xenopus oocytes.Distinct functions of Gq and G11 proteins in coupling alpha1-adrenoreceptors to Ca2+ release and Ca2+ entry in rat portal vein myocytes.Inhibition of IgE-induced mast cell activation by ethyl tertiary-butyl ether, a bioethanol-derived fuel oxygenate.Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors.Visualization of G protein betagamma dimers using bimolecular fluorescence complementation demonstrates roles for both beta and gamma in subcellular targeting.A highly effective dominant negative alpha s construct containing mutations that affect distinct functions inhibits multiple Gs-coupled receptor signaling pathways.The antidepressant imipramine inhibits M current by activating a phosphatidylinositol 4,5-bisphosphate (PIP2)-dependent pathway in rat sympathetic neurones.Expression of TRPC3 in Chinese hamster ovary cells results in calcium-activated cation currents not related to store depletion.The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho.Pasteurella multocida toxin activates the inositol triphosphate signaling pathway in Xenopus oocytes via G(q)alpha-coupled phospholipase C-beta1.
P2860
Q24290283-D540E650-EB68-4F81-A6A5-9B0FBD4B49F4Q24673814-ACC41CEB-7652-4353-A0E5-E3DA0C28BDD2Q28307111-F839E8F7-AD73-40B4-BD05-B73B26C09AD8Q28347748-7883ED45-6250-4BCE-A033-88B55EEF9170Q28593039-896CF503-A63B-4E1C-AEE3-815DBA05AB08Q30307133-B1866CBB-2CF4-41E6-8C9A-41AF59E46B02Q30471485-F3787F54-0529-4930-BB8F-97055C4E8215Q35627071-FAE82C28-187F-4614-87F7-2D1C88ED92A2Q36325794-C324671C-EE8C-4502-9098-14ECFC3A9881Q37731597-427D62A1-0B74-4528-889C-27A4B38CB638Q38309685-70F21BC3-4D98-43C2-BE5F-6268D497E65EQ38335240-0DC23657-F379-4404-96E1-6B60FFB1040EQ38348336-3CB663FE-A132-44D1-8FE3-5A8F8743A631Q39808949-58BFBF2B-D391-4D66-8AF7-D8458E83B3BFQ40126566-D651668E-6115-4167-9C10-44A58ED15138Q40557360-D0AEB3C4-2253-4287-BF9A-6885057E87D4Q40740952-AC364072-CD2C-4715-A867-514613937783Q42026209-50A13B1D-F2CD-4480-821C-A076933B3866Q42795855-DA23E52A-9904-4FE1-916C-C0EE477ED969Q42831845-7AEB9479-F912-4663-8557-CBE8CE66A3BCQ48965374-81D44D97-1A84-4032-955E-4B627160EBD7
P2860
A heterotrimeric G protein complex couples the muscarinic m1 receptor to phospholipase C-beta.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A heterotrimeric G protein com ...... eptor to phospholipase C-beta.
@en
A heterotrimeric G protein com ...... eptor to phospholipase C-beta.
@nl
type
label
A heterotrimeric G protein com ...... eptor to phospholipase C-beta.
@en
A heterotrimeric G protein com ...... eptor to phospholipase C-beta.
@nl
prefLabel
A heterotrimeric G protein com ...... eptor to phospholipase C-beta.
@en
A heterotrimeric G protein com ...... eptor to phospholipase C-beta.
@nl
P2093
P2860
P356
P1476
A heterotrimeric G protein com ...... eptor to phospholipase C-beta.
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.4.1391
P407
P577
1996-02-01T00:00:00Z