Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.
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Targeting innate immunity for neurodegenerative disorders of the central nervous systemNeuroinflammation in Alzheimer's diseaseCurcumin Ameliorates the Reduction Effect of PGE2 on Fibrillar β-Amyloid Peptide (1-42)-Induced Microglial Phagocytosis through the Inhibition of EP2-PKA Signaling in N9 Microglial CellsProstaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models.Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer's and Other Neurodegenerative Diseases.Microglial malfunction: the third rail in the development of Alzheimer's disease.Inflammatory Eicosanoids Increase Amyloid Precursor Protein Expression via Activation of Multiple Neuronal Receptors.Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-betaProstaglandin I₂ Attenuates Prostaglandin E₂-Stimulated Expression of Interferon γ in a β-Amyloid Protein- and NF-κB-Dependent MechanismCyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice.Untangling the Web: Toxic and Protective Effects of Neuroinflammation and PGE2 Signaling in Alzheimer's Disease.Inflammatory Cyclooxygenase Activity and PGE2 Signaling in Models of Alzheimer's DiseaseTargeting microglia for the treatment of Alzheimer's disease.Advances in the therapy of Alzheimer's disease: targeting amyloid beta and tau and perspectives for the future.The role of neuroinflammation in dementias.The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes.Dietary arachidonic acid increases deleterious effects of amyloid-β oligomers on learning abilities and expression of AMPA receptors: putative role of the ACSL4-cPLA2 balance.Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype.Prostaglandin E2 EP4 Receptor Activation Attenuates Neuroinflammation and Early Brain Injury Induced by Subarachnoid Hemorrhage in Rats.Anti-Inflammatory and Neuroprotective Effects of PGE2 EP4 Signaling in Models of Parkinson's Disease.Prostaglandin E2 potentiates interferon-γ-induced nitric oxide production in cultured rat microglia.Protective Effects of L-902,688, a Prostanoid EP4 Receptor Agonist, against Acute Blood-Brain Barrier Damage in Experimental Ischemic Stroke.Longitudinal influence of microglial activation and amyloid on neuronal function in Alzheimer's disease.Prostaglandin E2 Produced by Alginate-Encapsulated Mesenchymal Stromal Cells Modulates the Astrocyte Inflammatory Response.RNA sequencing analysis reveals quiescent microglia isolation methods from postnatal mouse brains and limitations of BV2 cells.Early Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic ReviewInflammation: the link between comorbidities, genetics, and Alzheimer's diseaseRiluzole reduces amyloid beta pathology, improves memory, and restores gene expression changes in a transgenic mouse model of early-onset Alzheimer's disease
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Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2014
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Suppression of Alzheimer-assoc ...... din-E2 EP4 receptor signaling.
@en
Suppression of Alzheimer-assoc ...... din-E2 EP4 receptor signaling.
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type
label
Suppression of Alzheimer-assoc ...... din-E2 EP4 receptor signaling.
@en
Suppression of Alzheimer-assoc ...... din-E2 EP4 receptor signaling.
@nl
prefLabel
Suppression of Alzheimer-assoc ...... din-E2 EP4 receptor signaling.
@en
Suppression of Alzheimer-assoc ...... din-E2 EP4 receptor signaling.
@nl
P2093
P2860
P921
P1476
Suppression of Alzheimer-assoc ...... ndin-E2 EP4 receptor signaling
@en
P2093
Irene Zagol-Ikapitte
Jenny U Johansson
Katrin I Andreasson
Olivier Boutaud
Paul Larkin
Prachi G Priyam
P2860
P304
P356
10.1523/JNEUROSCI.0410-14.2014
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P577
2014-04-01T00:00:00Z