Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo.
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Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cellsA screen for transcription factor targets of glycogen synthase kinase-3 highlights an inverse correlation of NFκB and androgen receptor signaling in prostate cancerActivation of glycogen synthase kinase 3β ameliorates diabetes-induced kidney injury.Discrete functions of GSK3α and GSK3β isoforms in prostate tumor growth and micrometastasis.Genetic deletion and pharmacological inhibition of Akt1 isoform attenuates bladder cancer cell proliferation, motility and invasion.Glycogen synthase kinase-3: a potential preventive target for prostate cancer managementLocal anesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro.Novel roles of Src in cancer cell epithelial-to-mesenchymal transition, vascular permeability, microinvasion and metastasis.Establishment and antitumor effects of dasatinib and PKI-587 in BD-138T, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant EGFR amplification and PTEN deletion.Pharmacology of Src family kinases and therapeutic implications of their modulators.Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer.Quantitative phosphoproteome analysis of embryonic stem cell differentiation toward bloodIn vivo regulation of glycogen synthase kinase 3β activity in neurons and brainsGlycogen Synthase Kinase 3α Is the Main Isoform That Regulates the Transcription Factors Nuclear Factor-Kappa B and cAMP Response Element Binding in Bovine Endothelial Cells Infected with Staphylococcus aureus.Suppression of Akt1-β-catenin pathway in advanced prostate cancer promotes TGFβ1-mediated epithelial to mesenchymal transition and metastasis.Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus.Cytokeratin 19 (KRT19) has a Role in the Reprogramming of Cancer Stem Cell-Like Cells to Less Aggressive and More Drug-Sensitive Cells.Modulation in the microRNA repertoire is responsible for the stage-specific effects of Akt suppression on murine neuroendocrine prostate cancer
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Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2014
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Targeting Src-mediated Tyr216 ...... gression in vitro and in vivo.
@en
Targeting Src-mediated Tyr216 ...... gression in vitro and in vivo.
@nl
type
label
Targeting Src-mediated Tyr216 ...... gression in vitro and in vivo.
@en
Targeting Src-mediated Tyr216 ...... gression in vitro and in vivo.
@nl
prefLabel
Targeting Src-mediated Tyr216 ...... gression in vitro and in vivo.
@en
Targeting Src-mediated Tyr216 ...... gression in vitro and in vivo.
@nl
P2093
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Targeting Src-mediated Tyr216 ...... gression in vitro and in vivo.
@en
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Alison Steinbach
Belal Al-Husein
David L DeRemer
Harika Sabbineni
Katerina Katsanevas
Payaningal R Somanath
Uvette Lou
P2860
P304
P356
10.18632/ONCOTARGET.1770
P407
P577
2014-02-01T00:00:00Z