Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.
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Basigin (CD147), a multifunctional transmembrane glycoprotein with various binding partnersHow, with whom and when: an overview of CD147-mediated regulatory networks influencing matrix metalloproteinase activityMetabolic reprogramming and metabolic dependency in T cellsThe role of EMMPRIN in T cell biology and immunological diseasesThe Retinal Specific CD147 Ig0 Domain: From Molecular Structure to Biological ActivityThe roles of CD147 and/or cyclophilin A in kidney diseasesFine tuning the inhibition profile of cyclosporine A by derivatization of the MeBmt residue.CD147, CD44, and the epidermal growth factor receptor (EGFR) signaling pathway cooperate to regulate breast epithelial cell invasiveness.EMMPRIN is secreted by human uterine epithelial cells in microvesicles and stimulates metalloproteinase production by human uterine fibroblast cellsCyclophilin B interacts with sodium-potassium ATPase and is required for pump activity in proximal tubule cells of the kidneyCyclophilin B facilitates the replication of Orf virus.The Rift Valley Fever virus protein NSm and putative cellular protein interactionsThe biological function and clinical utilization of CD147 in human diseases: a review of the current scientific literatureCyclophilin A (CyPA) induces chemotaxis independent of its peptidylprolyl cis-trans isomerase activity: direct binding between CyPA and the ectodomain of CD147Galectin-3 induces clustering of CD147 and integrin-β1 transmembrane glycoprotein receptors on the RPE cell surface.Inhibition of synovitis and joint destruction by a new single domain antibody specific for cyclophilin A in two different mouse models of rheumatoid arthritis.CD147 and MMP-9 expressions in type II/III adenocarcinoma of esophagogastric junction and their clinicopathological significances.Structure and Dynamics of GeoCyp: A Thermophilic Cyclophilin with a Novel Substrate Binding Mechanism That Functions Efficiently at Low Temperatures.Extracellular cyclophilin A possesses chemotaxic activity in cattle.Proteotoxic stress and circulating cell stress proteins in the cardiovascular diseases.Expression of CD147, PCNA, VEGF, MMPs and their clinical significance in the giant cell tumor of bones.The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells.Extracellular cyclophilin-A stimulates ERK1/2 phosphorylation in a cell-dependent manner but broadly stimulates nuclear factor kappa BThe protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging.A novel anti-EMMPRIN function-blocking antibody reduces T cell proliferation and neurotoxicity: relevance to multiple sclerosisKnockdown of EMMPRIN improves adverse remodeling mediated by IL-18 in the post-infarcted heartTargeting extracellular cyclophilins ameliorates disease progression in experimental biliary atresia.Effect of a quality-controlled fermented nutraceutical on skin aging markers: An antioxidant-control, double-blind studyA cell-impermeable cyclosporine A derivative reduces pathology in a mouse model of allergic lung inflammation.An epitope-specific novel anti-EMMPRIN polyclonal antibody inhibits tumor progression.Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure.Cyclophilin A from Schistosoma japonicum promotes a Th2 response in mice.HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s.Increased expression of extracellular matrix metalloproteinase inducer (CD147) in multiple myeloma: role in regulation of myeloma cell proliferationAcetylation of cyclophilin A is required for its secretion and vascular cell activationParticipation of 3-O-sulfated heparan sulfates in the protection of macrophages by herpes simplex virus-1 glycoprotein D and cyclophilin B against apoptosis.Melittin inhibits the invasion of MCF-7 cells by downregulating CD147 and MMP-9 expression.Basigin: a multifunctional membrane protein with an emerging role in infections by malaria parasites.Matrix metalloproteinase processing of signaling molecules to regulate inflammation.Monocarboxylic acid transport.
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Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 March 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.
@en
Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.
@nl
type
label
Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.
@en
Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.
@nl
prefLabel
Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.
@en
Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.
@nl
P2093
P2860
P1476
Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.
@en
P2093
E Eisenmesser
M Bukrinsky
S Constant
V Yurchenko
P2860
P304
P356
10.1111/J.1365-2249.2010.04115.X
P577
2010-03-16T00:00:00Z