A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation
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The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including AtherosclerosisInhaled hypertonic saline for cystic fibrosis: Reviewing the potential evidence for modulation of neutrophil signalling and functionRemodelling the extracellular matrix in development and diseaseMatrix metalloproteinases in inflammatory bowel disease: an updateNebulized hypertonic saline decreases IL-8 in sputum of patients with cystic fibrosisGenetic regulation of expression of leukotriene A4 hydrolaseThe expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patientsMatrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection.A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammationDiscoidin domain receptor 2 regulates neutrophil chemotaxis in 3D collagen matrices.N-Acetylated Proline-Glycine-Proline Accelerates Cutaneous Wound Healing and Neovascularization by Human Endothelial Progenitor CellsA novel lipidomic strategy reveals plasma phospholipid signatures associated with respiratory disease severity in cystic fibrosis patients.MMP-8 promotes polymorphonuclear cell migration through collagen barriers in obliterative bronchiolitisHuman neutrophil elastase-mediated cleavage sites of MMP-9 and TIMP-1: implications to cystic fibrosis proteolytic dysfunction.Targeting prolyl endopeptidase with valproic acid as a potential modulator of neutrophilic inflammationToll-Like Receptor 4 Engagement Mediates Prolyl Endopeptidase Release from Airway Epithelia via ExosomesCollagen-derived N-acetylated proline-glycine-proline upregulates the expression of pro-inflammatory cytokines and extracellular matrix proteases in nucleus pulposus cells via the NF-κB and MAPK signaling pathways.A self-propagating matrix metalloprotease-9 (MMP-9) dependent cycle of chronic neutrophilic inflammation.Prolyl oligopeptidase is inhibited in relapsing-remitting multiple sclerosis.Proline-Glycine-Proline (PGP) and High Mobility Group Box Protein-1 (HMGB1): Potential Mediators of Cystic Fibrosis Airway Inflammation.Robust substrate profiling method reveals striking differences in specificities of serum and lung fluid proteases.Early elevation of matrix metalloproteinase-8 and -9 in pediatric ARDS is associated with an increased risk of prolonged mechanical ventilation.Identification of Novel Therapeutic Targets in COPD.Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors.The presence of a matrix-derived neutrophil chemoattractant in bronchiolitis obliterans syndrome after lung transplantation.An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary diseaseInhibition of lung serine proteases in mice: a potentially new approach to control influenza infection.Prolyl endopeptidase activity in bronchoalveolar lavage fluid: a novel diagnostic biomarker in a guinea pig model of invasive pulmonary aspergillosis.Cigarette smoke-induced collagen destruction; key to chronic neutrophilic airway inflammation?Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown.Pulmonary proteases in the cystic fibrosis lung induce interleukin 8 expression from bronchial epithelial cells via a heme/meprin/epidermal growth factor receptor/Toll-like receptor pathway.CD14 signaling reciprocally controls collagen deposition and turnover to regulate the development of lyme arthritis.Increased expression of matrix metalloproteinase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunction.Plasma lipidomics reveals potential prognostic signatures within a cohort of cystic fibrosis patients.Matrix metalloproteinase-1 polymorphism (-1607G) and disease severity in non-cystic fibrosis bronchiectasis in TaiwanIdentification of neutrophil activation markers as novel surrogate markers of CF lung disease.Prolyl oligopeptidase induces angiogenesis both in vitro and in vivo in a novel regulatory manner.Integrated extracellular matrix signaling in mammary gland development and breast cancer progression.Potential of anti-inflammatory treatment for cystic fibrosis lung disease.Host-pathogen interplay in the respiratory environment of cystic fibrosis.
P2860
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P2860
A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A novel proteolytic cascade ge ...... onic neutrophilic inflammation
@en
A novel proteolytic cascade ge ...... nic neutrophilic inflammation.
@nl
type
label
A novel proteolytic cascade ge ...... onic neutrophilic inflammation
@en
A novel proteolytic cascade ge ...... nic neutrophilic inflammation.
@nl
prefLabel
A novel proteolytic cascade ge ...... onic neutrophilic inflammation
@en
A novel proteolytic cascade ge ...... nic neutrophilic inflammation.
@nl
P2093
P2860
P921
P1476
A novel proteolytic cascade ge ...... onic neutrophilic inflammation
@en
P2093
Amit Gaggar
Brett D Noerager
D Brent McQuaid
J Edwin Blalock
J P Clancy
Patricia L Jackson
Philip J O'Reilly
Steven M Rowe
P2860
P304
P356
10.4049/JIMMUNOL.180.8.5662
P407
P577
2008-04-01T00:00:00Z