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Emerging Roles of Filopodia and Dendritic Spines in Motoneuron Plasticity during Development and DiseaseGenerating Diverse Spinal Motor Neuron Subtypes from Human Pluripotent Stem CellsFactors influencing the spinal motoneurons in developmentStem cell transplantation for motor neuron disease: current approaches and future perspectivesEphrin-A3 promotes and maintains slow muscle fiber identity during postnatal development and reinnervation.Modeling ALS with motor neurons derived from human induced pluripotent stem cellsEmerging mechanisms of molecular pathology in ALSNeuronal matrix metalloproteinase-9 is a determinant of selective neurodegenerationGDE2 regulates subtype-specific motor neuron generation through inhibition of Notch signalingDevelopment-on-chip: in vitro neural tube patterning with a microfluidic deviceLarge-Scale Production of Mature Neurons from Human Pluripotent Stem Cells in a Three-Dimensional Suspension Culture SystemSensorimotor function is modulated by the serotonin receptor 1d, a novel marker for gamma motor neuronsViral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo.A compartmentalized microfluidic neuromuscular co-culture system reveals spatial aspects of GDNF functionsMonitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging.c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis.CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs.Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy.Core promoter factor TAF9B regulates neuronal gene expression.Induced neuronal reprogramming.Development-inspired reprogramming of the mammalian central nervous system.Necroptosis drives motor neuron death in models of both sporadic and familial ALS.Functional diversity of ESC-derived motor neuron subtypes revealed through intraspinal transplantation.Retrograde influence of muscle fibers on their innervation revealed by a novel marker for slow motoneuronsPlasticity versus specificity in RTK signalling modalities for distinct biological outcomes in motor neurons.IH activity is increased in populations of slow versus fast motor axons of the ratGas7-deficient mouse reveals roles in motor function and muscle fiber composition during aging.Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures.7,8-Dihydroxyflavone improves motor performance and enhances lower motor neuronal survival in a mouse model of amyotrophic lateral sclerosis.Early functional impairment of sensory-motor connectivity in a mouse model of spinal muscular atrophy.eGFP expression under UCHL1 promoter genetically labels corticospinal motor neurons and a subpopulation of degeneration-resistant spinal motor neurons in an ALS mouse model.What can pluripotent stem cells teach us about neurodegenerative diseases?Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state.Enhanced neuronal Met signalling levels in ALS mice delay disease onset.Motor neuron trophic factors: therapeutic use in ALS?IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1.SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice.Structural and kinetic analysis of protein-aggregate strains in vivo using binary epitope mappingFoxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells.Elevated mRNA-levels of distinct mitochondrial and plasma membrane Ca(2+) transporters in individual hypoglossal motor neurons of endstage SOD1 transgenic mice.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Motor neuron diversity in development and disease.
@en
Motor neuron diversity in development and disease.
@nl
type
label
Motor neuron diversity in development and disease.
@en
Motor neuron diversity in development and disease.
@nl
prefLabel
Motor neuron diversity in development and disease.
@en
Motor neuron diversity in development and disease.
@nl
P2093
P1476
Motor neuron diversity in development and disease.
@en
P2093
Artem Kaplan
Christopher E Henderson
Kevin C Kanning
P304
P356
10.1146/ANNUREV.NEURO.051508.135722
P577
2010-01-01T00:00:00Z