Drug-induced ion channel opening tuned by the voltage sensor charge profile.
about
In-Depth Study of the Interaction, Sensitivity, and Gating Modulation by PUFAs on K+ Channels; Interaction and New TargetsResin-acid derivatives as potent electrostatic openers of voltage-gated K channels and suppressors of neuronal excitabilityPolyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channelActivation of peripheral KCNQ channels relieves gout pain.Electronic polymers in lipid membranes.The Molecular Basis of Polyunsaturated Fatty Acid Interactions with the Shaker Voltage-Gated Potassium ChannelAlkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening.Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation.Atomic determinants of BK channel activation by polyunsaturated fatty acids.Actions and Mechanisms of Polyunsaturated Fatty Acids on Voltage-Gated Ion Channels.Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel.Isopimaric acid - a multi-targeting ion channel modulator reducing excitability and arrhythmicity in a spontaneously beating mouse atrial cell line.Extracellular Linkers Completely Transplant the Voltage Dependence from Kv1.2 Ion Channels to Kv2.1.A drug pocket at the lipid bilayer-potassium channel interface.Atom-by-atom tuning of the electrostatic potassium-channel modulator dehydroabietic acid.Mechanisms Underlying the Dual Effect of Polyunsaturated Fatty Acid Analogs on Kv7.1
P2860
Q28066803-A58F9DCC-841A-4215-9EB6-0970FF16DBFDQ30989304-58C9296E-9965-4525-A83C-F2B28FCCE44CQ35590205-3D9E1E56-97DD-436A-BBA1-B578CF47F15AQ35670568-CAAC3CCF-2E53-4DA6-B8CB-39FE35E33956Q35710409-14AF757D-B2F1-4145-A178-0E27E7F51E0BQ35890108-79D40971-174D-4711-9411-61FD9389A540Q36330508-147B7B44-E3A2-4234-98C2-37F804F1CA11Q36985914-B249764B-9683-4D23-990E-3F03CDBCEB23Q37473820-0810174F-BEB3-4FBC-B278-4137028DE1E2Q37625453-EB62D9B4-D6E6-4672-9706-5779ABF44A7BQ37735820-909763FF-CE36-4C70-BCCE-B9BC485DBE88Q38703225-8BABE4CB-09FC-4914-BDE5-DEBF23CB1EDBQ39270503-247803AC-B8D2-4E0D-84EF-BFD2516E8300Q42631347-C77D205C-8499-4A67-ADC8-A69864D02352Q53832064-840B44FB-8447-47E1-8A79-BA8436AA7105Q58749124-08E80BFD-11A4-40EF-9AD4-4B0E14BF8B1F
P2860
Drug-induced ion channel opening tuned by the voltage sensor charge profile.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 January 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Drug-induced ion channel opening tuned by the voltage sensor charge profile.
@en
Drug-induced ion channel opening tuned by the voltage sensor charge profile.
@nl
type
label
Drug-induced ion channel opening tuned by the voltage sensor charge profile.
@en
Drug-induced ion channel opening tuned by the voltage sensor charge profile.
@nl
prefLabel
Drug-induced ion channel opening tuned by the voltage sensor charge profile.
@en
Drug-induced ion channel opening tuned by the voltage sensor charge profile.
@nl
P2860
P356
P1476
Drug-induced ion channel opening tuned by the voltage sensor charge profile.
@en
P2093
Nina E Ottosson
P2860
P304
P356
10.1085/JGP.201311087
P577
2014-01-13T00:00:00Z