Discovery of N-(3,5-bis(1-pyrrolidylmethyl)-4-hydroxybenzyl)-4-methoxybenzenesulfamide (sulcardine) as a novel anti-arrhythmic agent.
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Emergence of Chinese drug discovery research: impact of hit and lead identification.Determination of the novel antiarrhythmic drug sulcardine sulfate in human plasma by liquid chromatography tandem mass spectrometry and its application in a clinical pharmacokinetic study.Oral Bioavailability and Mass Balance Studies of a Novel Anti-arrhythmic Agent Sulcardine Sulfate in Sprague-Dawley Rats and Beagle Dogs.Celebrating the 80th anniversary of the Shanghai Institute of Materia Medica, Chinese Academy of Sciences (SIMM).Barbaloin inhibits ventricular arrhythmias in rabbits by modulating voltage-gated ion channels.Pharmacokinetics, safety, and tolerability of sulcardine sulfate: an open-label, single-dose, randomized study in healthy Chinese subjects.
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Discovery of N-(3,5-bis(1-pyrrolidylmethyl)-4-hydroxybenzyl)-4-methoxybenzenesulfamide (sulcardine) as a novel anti-arrhythmic agent.
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article científic
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artigo científico
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scientific article published on 27 August 2012
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vedecký článok
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vetenskaplig artikel
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Discovery of N-(3,5-bis(1-pyrr ...... a novel anti-arrhythmic agent.
@en
Discovery of N-(3,5-bis(1-pyrr ...... a novel anti-arrhythmic agent.
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label
Discovery of N-(3,5-bis(1-pyrr ...... a novel anti-arrhythmic agent.
@en
Discovery of N-(3,5-bis(1-pyrr ...... a novel anti-arrhythmic agent.
@nl
prefLabel
Discovery of N-(3,5-bis(1-pyrr ...... a novel anti-arrhythmic agent.
@en
Discovery of N-(3,5-bis(1-pyrr ...... a novel anti-arrhythmic agent.
@nl
P2093
P2860
P356
P1476
Discovery of N-(3,5-bis(1-pyrr ...... a novel anti-arrhythmic agent.
@en
P2093
Ai-Li Kang
Dong-Lu Bai
Wei-Kang Sun
Wei-Zhou Chen
Yi-Ping Wang
Yue-Li Dong
Yun-Xin Bo
Zhong-Liang Hu
P2860
P2888
P304
P356
10.1038/APS.2012.119
P577
2012-08-27T00:00:00Z