Mutation of cysteine-88 in the Saccharomyces cerevisiae RAD6 protein abolishes its ubiquitin-conjugating activity and its various biological functions.
about
Regulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylationRAD6B overexpression confers chemoresistance: RAD6 expression during cell cycle and its redistribution to chromatin during DNA damage-induced responseDominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphaseRole of UEV-1, an inactive variant of the E2 ubiquitin-conjugating enzymes, in in vitro differentiation and cell cycle behavior of HT-29-M6 intestinal mucosecretory cells.Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6The products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein familySupramolecular complex formation between Rad6 and proteins of the p53 pathway during DNA damage-induced responseEvidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasomeCrystal structure of the Saccharomyces cerevisiae ubiquitin-conjugating enzyme Rad6 at 2.6 A resolutionThe DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1.MMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathwayThe ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae.Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair.Yeast N-terminal amidase. A new enzyme and component of the N-end rule pathway.Direct Bre1-Paf1 complex interactions and RING finger-independent Bre1-Rad6 interactions mediate histone H2B ubiquitylation in yeastYeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities.Overexpression of VrUBC1, a Mung Bean E2 Ubiquitin-Conjugating Enzyme, Enhances Osmotic Stress Tolerance in ArabidopsisModification of Ran GTPase-activating protein by the small ubiquitin-related modifier SUMO-1 requires Ubc9, an E2-type ubiquitin-conjugating enzyme homologueMolecular cloning, expression and characterization of a ubiquitin conjugation enzyme (E2(17)kB) highly expressed in rat testisThe ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeastControl of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugationElevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes.Cloning and characterization of a 20-kDa ubiquitin carrier protein from wheat that catalyzes multiubiquitin chain formation in vitroReplication-dependent and -independent responses of RAD18 to DNA damage in human cells.Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1.Degradation or maintenance: actions of the ubiquitin system on eukaryotic chromatinRad6 is a Potential Early Marker of Melanoma DevelopmentRegulation of gross chromosomal rearrangements by ubiquitin and SUMO ligases in Saccharomyces cerevisiae.Transcriptional silencing in Saccharomyces cerevisiae and Schizosaccharomyces pombe.Role of Saccharomyces cerevisiae chromatin assembly factor-I in repair of ultraviolet radiation damage in vivoUbiquitin-mediated protein modification and degradation.RAD6 regulates the dosage of p53 by a combination of transcriptional and posttranscriptional mechanismsYeast RAD6 encoded ubiquitin conjugating enzyme mediates protein degradation dependent on the N-end-recognizing E3 enzymeSuffering in silence: the tolerance of DNA damage.Incubation at the nonpermissive temperature induces deficiencies in UV resistance and mutagenesis in mouse mutant cells expressing a temperature-sensitive ubiquitin-activating enzyme (E1)Gold nanoparticle conjugated Rad6 inhibitor induces cell death in triple negative breast cancer cells by inducing mitochondrial dysfunction and PARP-1 hyperactivation: Synthesis and characterization.E6AP/UBE3A ubiquitin ligase harbors two E2~ubiquitin binding sites.Cloning of a novel ubiquitin-conjugating enzyme (E2) gene from the ciliate Paramecium tetraurelia.Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6.
P2860
Q24294393-2B8D8D0D-02F5-4721-AD60-78348DAF4D41Q24311807-F996F22C-A91F-4CD8-A14C-0D7ED60F2F11Q24317284-6EBBB941-BD04-4038-AFCB-22BEB341351DQ24317608-63392549-6787-4C1D-95B1-22C9688CD143Q24337556-899BD945-F9B9-46F7-840B-45DDCFA9A8E7Q24548218-D7D57D89-6907-4A92-8E38-A6A6462E9084Q24551106-41DF743E-7648-4663-81C6-19261C9B8C74Q24554092-28DEB49D-B2FC-4580-B397-8CCB84147E39Q27748912-B59AD89A-468A-4593-BE1C-0AE393AE0AADQ27934025-0F68AABB-62D4-43DD-A408-996935B005F6Q27934604-624D6EB0-1DE4-4B4A-82E1-C9896996324CQ27934959-E5642A93-C65B-40D2-90ED-501B231AFDB3Q27935427-10DB3E6E-18E0-4568-BB4D-8274537AB7ADQ27936521-BC30CBE4-A16D-4DD3-AF0F-EC25D6F7E159Q27936986-99D9AD1B-63CA-4384-B0D3-8D045EF1AFDCQ27938794-C9E94752-F75D-4895-A6AD-63F7A8EA8DE4Q28534078-3CF9C958-6D6F-49BD-823A-54AF8A566B98Q28577849-818AFBC1-A18F-446A-87AF-C405D0261D07Q28580225-98B47866-300C-4701-8C94-64A1EB041BBCQ28587712-0DB0075D-3261-4B40-8F28-FE8D6FE90693Q29617217-7953DEC7-70ED-4D55-A6DC-6ECC1A03216FQ29619155-CE23D165-78CC-4553-A8B7-BA776DB04D39Q30307758-6DBE3FB6-E606-49F2-A9FB-C9AA06020BE1Q33238681-7DBC1572-16DB-4152-B0EC-0178FF0E421FQ33257837-FC2354D6-C9C8-4C20-B700-72C3DA84E259Q33513306-82EBF03C-8879-47A2-ABF4-51BBC5E0B822Q33905811-FD395206-1A26-4A10-AA80-66C35C4E452EQ34092180-559AF980-F904-4C26-B5EF-9C6C4B0D0AF0Q34353641-CDAD0DCB-04EA-48F8-87C0-BA62E026B3E0Q34578729-D60EFC10-30E5-42EF-AE22-60048B411F5DQ34606378-C3B7149F-06E9-4C26-A379-D01B881A849BQ35234707-51D0CABD-EE2E-42D5-A9D2-57AE3BEF31FBQ35665695-90C936AA-712B-48D4-BB27-E50C17600579Q35928237-2C06ED73-B070-4925-A032-BA8610BBBC3EQ36337954-03D9219F-E7D4-4E16-BAA3-C9335CE6F0FEQ36565973-4AED2E84-0BD6-45F1-B611-348B05AA996CQ36734488-4D531408-F846-4070-A05B-E7382BF9F88CQ36760286-BBFC2C25-CC27-42C2-80CF-CB882793D1EDQ36807877-DE767BC0-3A72-4AFC-97F9-F74CB4DB0A5EQ37499986-543D68F8-BAB8-43B3-8F80-D23D8826C939
P2860
Mutation of cysteine-88 in the Saccharomyces cerevisiae RAD6 protein abolishes its ubiquitin-conjugating activity and its various biological functions.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mutation of cysteine-88 in the ...... various biological functions.
@en
Mutation of cysteine-88 in the ...... various biological functions.
@nl
type
label
Mutation of cysteine-88 in the ...... various biological functions.
@en
Mutation of cysteine-88 in the ...... various biological functions.
@nl
prefLabel
Mutation of cysteine-88 in the ...... various biological functions.
@en
Mutation of cysteine-88 in the ...... various biological functions.
@nl
P2093
P2860
P356
P1476
Mutation of cysteine-88 in the ...... various biological functions.
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.7.2695
P407
P577
1990-04-01T00:00:00Z