Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts
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Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner.Targeting Epigenetic Aberrations in Pancreatic Cancer, a New Path to Improve Patient Outcomes?Bromodomain protein BRD4 inhibitor JQ1 regulates potential prognostic molecules in advanced renal cell carcinoma.E2F signature is predictive for the pancreatic adenocarcinoma clinical outcome and sensitivity to E2F inhibitors, but not for the response to cytotoxic-based treatments.Modeling combination therapy for breast cancer with BET and immune checkpoint inhibitorsFBP1 loss contributes to BET inhibitors resistance by undermining c-Myc expression in pancreatic ductal adenocarcinoma
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Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 March 2017
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Gene expression profiling of p ...... ndividualized medicine efforts
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Gene expression profiling of p ...... dividualized medicine efforts.
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Gene expression profiling of p ...... ndividualized medicine efforts
@en
Gene expression profiling of p ...... dividualized medicine efforts.
@nl
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Gene expression profiling of p ...... ndividualized medicine efforts
@en
Gene expression profiling of p ...... dividualized medicine efforts.
@nl
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P2860
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Gene expression profiling of p ...... ndividualized medicine efforts
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P2093
Andres Saul
Aurélie Maignan
Celine Loncle
Gwen Lomberk
James E Bradner
Jean-Luc Raoul
Laetitia Marisa
Marc Giovannini
Marine Gilabert
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P304
P356
10.15252/EMMM.201606975
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2017-03-08T00:00:00Z