Proliferation of latently infected CD4+ T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics.
about
Landscape review of current HIV 'kick and kill' cure research - some kicking, not enough killing.HIV persistence: clonal expansion of cells in the latent reservoir.Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells.Dendritic cells as natural latency reversing agent: a wake-up call for HIV-1.No evidence of HIV replication in children on antiretroviral therapy.Differentiating Immune Cell Targets in Gut-Associated Lymphoid Tissue for HIV Cure.Relative efficacy of T cell stimuli as inducers of productive HIV-1 replication in latently infected CD4 lymphocytes from patients on suppressive cART.HIV: Persistence through division.The mouse viral outgrowth assay: avatars for the detection of HIV-1 reservoirs.Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants.Modeling Kick-Kill Strategies toward HIV Cure.Innovations in the quantitative virus outgrowth assay and its use in clinical trials.Pegylated IFN-α-induced NK cell activation is associated with HIV-1 DNA decline in ART-treated HIV-1/HCV co-infected patients.HIV integration sites and implications for maintenance of the reservoir.HIV evolution and diversity in ART-treated patients.Hepatitis B Virus Vaccination in HIV-1-Infected Young Adults: A Tool to Reduce the Size of HIV-1 Reservoirs?Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells.Effect of analytical treatment interruption and reinitiation of antiretroviral therapy on HIV reservoirs and immunologic parameters in infected individuals.Towards a cure for human immunodeficiency virus.Recent progress in understanding HIV reservoirs.Lorenzo-Redondo et al. reply.Mathematical Models of HIV Latency.Harnessing Novel Imaging Approaches to Guide HIV Prevention and Cure Discoveries-A National Institutes of Health and Global HIV Vaccine Enterprise 2017 Meeting Report.Assays to Measure Latency, Reservoirs, and Reactivation.Measuring replication competent HIV-1: advances and challenges in defining the latent reservoir.No evidence of ongoing evolution in replication competent latent HIV-1 in a patient followed up for two years.Re-evaluating evolution in the HIV reservoir.Trade-off between synergy and efficacy in combinations of HIV-1 latency-reversing agents.Visualizing the Immune System: Providing Key Insights into HIV/SIV Infections.Clonal CD4+ T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation.Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane.Quantitation of the latent HIV-1 reservoir from the sequence diversity in viral outgrowth assays.HLA-C downregulation by HIV-1 adapts to host HLA genotypeMyeloid Dendritic Cells Induce HIV Latency in Proliferating CD4 T CellsCombination therapy with anti-HIV-1 antibodies maintains viral suppressionLong-term remission despite clonal expansion of replication-competent HIV-1 isolatesA majority of HIV persistence during antiretroviral therapy is due to infected cell proliferation
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Proliferation of latently infected CD4+ T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 March 2017
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Proliferation of latently infe ...... in latent reservoir dynamics.
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Proliferation of latently infe ...... in latent reservoir dynamics.
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type
label
Proliferation of latently infe ...... in latent reservoir dynamics.
@en
Proliferation of latently infe ...... in latent reservoir dynamics.
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prefLabel
Proliferation of latently infe ...... in latent reservoir dynamics.
@en
Proliferation of latently infe ...... in latent reservoir dynamics.
@nl
P2093
P2860
P50
P356
P1476
Proliferation of latently infe ...... in latent reservoir dynamics.
@en
P2093
Adam A Capoferri
Brandon F Keele
Daniel I S Rosenbloom
Katherine M Bruner
Kyungyoon J Kwon
Nina N Hosmane
P2860
P304
P356
10.1084/JEM.20170193
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P577
2017-03-24T00:00:00Z