Production of pharmaceutical-grade recombinant aprotinin and a monoclonal antibody product using plant-based transient expression systems.
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Rapid and scalable plant-based production of a cholera toxin B subunit variant to aid in mass vaccination against cholera outbreaksDelayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaquesEnvironment Control to Improve Recombinant Protein Yields in Plants Based on Agrobacterium-Mediated Transient Gene ExpressionCommercial-scale biotherapeutics manufacturing facility for plant-made pharmaceuticalsPlant-based solutions for veterinary immunotherapeutics and prophylacticsGene delivery into plant cells for recombinant protein production.The Last Ten Years of Advancements in Plant-Derived Recombinant Vaccines against Hepatitis BEnhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant.Manufacturing economics of plant-made biologics: case studies in therapeutic and industrial enzymes.Prevention and treatment of Clostridium perfringens epsilon toxin intoxication in mice with a neutralizing monoclonal antibody (c4D7) produced in Nicotiana benthamiana.Post-translational regulation and trafficking of the granulin-containing protease RD21 of Arabidopsis thaliana.N-glycosylation of cholera toxin B subunit in Nicotiana benthamiana: impacts on host stress response, production yield and vaccine potential.Emerging antibody products and Nicotiana manufacturing.Production and characterization of in planta transiently produced polygalacturanase from Aspergillus niger and its fusions with hydrophobin or ELP tagsExploring the pharmacological potential of promiscuous host-defense peptides: from natural screenings to biotechnological applications.Plant-based expression of a partially humanized neutralizing monoclonal IgG directed against an immunodominant epitope on the ricin toxin A subunit.Lepidopteran cells, an alternative for the production of recombinant antibodies?Synthetic human monoclonal antibodies toward staphylococcal enterotoxin B (SEB) protective against toxic shock syndromeEfficient single tobamoviral vector-based bioproduction of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 in Nicotiana benthamiana plants and utility of VRC01 in combination microbicidesMonoclonal antibody therapy for Junin virus infection.Transient Expression of Tetrameric Recombinant Human Butyrylcholinesterase in Nicotiana benthamiana.Comparison of Expression Vectors for Transient Expression of Recombinant Proteins in Plants.Prophylactic and therapeutic testing of Nicotiana-derived RSV-neutralizing human monoclonal antibodies in the cotton rat model.Glyco-engineering in plants to produce human-like N-glycan structures.Multiantibody strategies for HIV.Transient co-expression of post-transcriptional gene silencing suppressors for increased in planta expression of a recombinant anthrax receptor fusion protein.Polyclonal antibodies for specific detection of tobacco host cell proteins can be efficiently generated following RuBisCO depletion and the removal of endotoxins.In plant activation: an inducible, hyperexpression platform for recombinant protein production in plants.Comparative in vitro and experimental in vivo studies of the anti-epidermal growth factor receptor antibody nimotuzumab and its aglycosylated form produced in transgenic tobacco plants.Engineering mammalian mucin-type O-glycosylation in plants.Removal of bacterial suspension water occupying the intercellular space of detached leaves after agroinfiltration improves the yield of recombinant hemagglutinin in a Nicotiana benthamiana transient gene expression system.From gene to harvest: insights into upstream process development for the GMP production of a monoclonal antibody in transgenic tobacco plants.Identification of the subgenomic promoter of the coat protein gene of cucumber fruit mottle mosaic virus and development of a heterologous expression vector.Production of Recombinant Cholera Toxin B Subunit in Nicotiana benthamiana Using GENEWARE® Tobacco Mosaic Virus Vector.Expression of functionally active sialylated human erythropoietin in plantsA Narcissus mosaic viral vector system for protein expression and flavonoid productionMedia development for large scale Agrobacterium tumefaciens culture.Antibody purification via affinity membrane chromatography method utilizing nucleotide binding site targeting with a small molecule.Animal component-free Agrobacterium tumefaciens cultivation media for better GMP-compliance increases biomass yield and pharmaceutical protein expression in Nicotiana benthamiana.Growth kinetics and scale-up of Agrobacterium tumefaciens.
P2860
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P2860
Production of pharmaceutical-grade recombinant aprotinin and a monoclonal antibody product using plant-based transient expression systems.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Production of pharmaceutical-g ...... transient expression systems.
@en
Production of pharmaceutical-g ...... transient expression systems.
@nl
type
label
Production of pharmaceutical-g ...... transient expression systems.
@en
Production of pharmaceutical-g ...... transient expression systems.
@nl
prefLabel
Production of pharmaceutical-g ...... transient expression systems.
@en
Production of pharmaceutical-g ...... transient expression systems.
@nl
P2093
P1476
Production of pharmaceutical-g ...... d transient expression systems
@en
P2093
Barry Bratcher
Earl White
Ernie Hiatt
Fakhrieh Vojdani
Gregory P Pogue
Hugh Haydon
Jesus Velasco
Jim Phelps
Kevin Whaley
P304
P356
10.1111/J.1467-7652.2009.00495.X
P577
2010-06-01T00:00:00Z