Focal adhesion kinase and p53 signal transduction pathways in cancer.
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p53 in cell invasion, podosomes, and invadopodiaReceptor-interacting protein kinase 2 promotes triple-negative breast cancer cell migration and invasion via activation of nuclear factor-kappaB and c-Jun N-terminal kinase pathways.Contribution of p53 to metastasis.Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth.Collagen density regulates xenobiotic and hypoxic response of mammary epithelial cellsFocal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival.Antroquinonol Targets FAK-Signaling Pathway Suppressed Cell Migration, Invasion, and Tumor Growth of C6 Glioma.Identification of genes associated with laryngeal squamous cell carcinoma samples based on bioinformatic analysis.Integrated analysis of miRNA, gene, and pathway regulatory networks in hepatic cancer stem cells.TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell deathNanog increases focal adhesion kinase (FAK) promoter activity and expression and directly binds to FAK protein to be phosphorylated.High-throughput screening strategies for targeted identification of therapeutic compounds in colorectal cancer.cAMP Elevation Down-Regulates β3 Integrin and Focal Adhesion Kinase and Inhibits Leptin-Induced Migration of MDA-MB-231 Breast Cancer Cells.Pharmacologic blockade of FAK autophosphorylation decreases human glioblastoma tumor growth and synergizes with temozolomide.A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.Genomic profiling in locally advanced and inflammatory breast cancer and its link to DCE-MRI and overall survival.Targeting the p53 pathway.Focal adhesion complex proteins in epidermis and squamous cell carcinoma.Ambivalent role of pFAK-Y397 in serous ovarian cancer--a study of the OVCAD consortium.FAK and p53 protein interactions.Role of ion transport in control of apoptotic cell death.Targeting angiogenesis and the tumor microenvironment.Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex.The microarray gene profiling analysis of glioblastoma cancer cells reveals genes affected by FAK inhibitor Y15 and combination of Y15 and temozolomide.Therapeutic upregulation of Class A scavenger receptor member 5 inhibits tumor growth and metastasis.Anti-metastatic effect of jolkinolide B and the mechanism of activity in breast cancer MDA-MB-231 cells.The Misregulation of Cell Adhesion Components during Tumorigenesis: Overview and Commentary.Doxycycline inhibits leukemic cell migration via inhibition of matrix metalloproteinases and phosphorylation of focal adhesion kinaseDietary selenomethionine increases exon-specific DNA methylation of the p53 gene in rat liver and colon mucosa.High FAK combined with low JWA expression: clinical prognostic and predictive role for adjuvant fluorouracil-leucovorin-oxaliplatin treatment in resectable gastric cancer patients.Myoepithelial and luminal breast cancer cells exhibit different responses to all-trans retinoic acid.Inhibition of cell migration by focal adhesion kinase: Time-dependent difference in integrin-induced signaling between endothelial and hepatoblastoma cells.Activating mutations of GNAS in canine cortisol-secreting adrenocortical tumors.The expression of RKIP, RhoGDI, galectin, c-Myc and p53 in gastrointestinal system of Cr(VI)-exposed rats.Plakoglobin restores tumor suppressor activity of p53R175H mutant by sequestering the oncogenic potential of β-catenin.
P2860
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P2860
Focal adhesion kinase and p53 signal transduction pathways in cancer.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on June 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Focal adhesion kinase and p53 signal transduction pathways in cancer.
@en
Focal adhesion kinase and p53 signal transduction pathways in cancer.
@nl
type
label
Focal adhesion kinase and p53 signal transduction pathways in cancer.
@en
Focal adhesion kinase and p53 signal transduction pathways in cancer.
@nl
prefLabel
Focal adhesion kinase and p53 signal transduction pathways in cancer.
@en
Focal adhesion kinase and p53 signal transduction pathways in cancer.
@nl
P2860
P356
P1476
Focal adhesion kinase and p53 signal transduction pathways in cancer.
@en
P2093
Vita M Golubovskaya
William Cance
P2860
P304
P356
10.2741/3653
P577
2010-06-01T00:00:00Z