Cell membrane permeabilization via connexin hemichannels in living and dying cells.
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Connexin and Pannexin hemichannels are regulated by redox potentialDiseases associated with leaky hemichannelsRelevance of gap junctions and large pore channels in traumatic brain injuryNeuronal gap junctions: making and breaking connections during development and injuryGap junctionsMotifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensingAberrant Cx26 hemichannels and keratitis-ichthyosis-deafness syndrome: insights into syndromic hearing lossKeratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43.Distinct permeation profiles of the connexin 30 and 43 hemichannelsRegulation of cellular communication by signaling microdomains in the blood vessel wall.The Cx26-G45E mutation displays increased hemichannel activity in a mouse model of the lethal form of keratitis-ichthyosis-deafness syndrome.Cx46 hemichannels contribute to the sodium leak conductance in lens fiber cellsOpening of pannexin- and connexin-based channels increases the excitability of nodose ganglion sensory neurons.Pathogenic connexin-31 forms constitutively active hemichannels to promote necrotic cell deathThe role of gap junction channels during physiologic and pathologic conditions of the human central nervous systemRhoA GTPase switch controls Cx43-hemichannel activity through the contractile systemMutations in cardiovascular connexin genes.Carbon monoxide (CO) is a novel inhibitor of connexin hemichannels.Prolonged minocycline treatment impairs motor neuronal survival and glial function in organotypic rat spinal cord cultures.The connexin46 mutant, Cx46T19M, causes loss of gap junction function and alters hemi-channel gatingBiphasic effect of linoleic acid on connexin 46 hemichannels.HIV increases the release of dickkopf-1 protein from human astrocytes by a Cx43 hemichannel-dependent mechanismCalcium entry via connexin hemichannels in lens epitheliumFunctional hemichannels formed by human connexin 26 expressed in bacteriaThe importance of connexin hemichannels during chondroprogenitor cell differentiation in hydrogel versus microtissue culture models.Sodium channels in the Cx43 gap junction perinexus may constitute a cardiac ephapse: an experimental and modeling study.Connexin and pannexin channels in cancer.Biological role of connexin intercellular channels and hemichannelsConnexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotectionGap junctions and hemichannels: communicating cell death in neurodevelopment and diseaseHuman articular chondrocytes express multiple gap junction proteins: differential expression of connexins in normal and osteoarthritic cartilageMechanism of Mitochondrial Connexin43's Protection of the Neurovascular Unit under Acute Cerebral Ischemia-Reperfusion Injury.Insights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y).Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles.Possible involvement of TLRs and hemichannels in stress-induced CNS dysfunction via mastocytes, and glia activation.Pannexin1 hemichannels are critical for HIV infection of human primary CD4+ T lymphocytes.A novel homozygous mutation in the EC1/EC2 interaction domain of the gap junction complex connexon 26 leads to profound hearing impairmentConnexins form functional hemichannels in porcine ciliary epithelium.Roles and regulation of lens epithelial cell connexins.Pathological hemichannels associated with human Cx26 mutations causing Keratitis-Ichthyosis-Deafness syndrome.
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P2860
Cell membrane permeabilization via connexin hemichannels in living and dying cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 June 2010
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Cell membrane permeabilization via connexin hemichannels in living and dying cells.
@en
Cell membrane permeabilization via connexin hemichannels in living and dying cells.
@nl
type
label
Cell membrane permeabilization via connexin hemichannels in living and dying cells.
@en
Cell membrane permeabilization via connexin hemichannels in living and dying cells.
@nl
prefLabel
Cell membrane permeabilization via connexin hemichannels in living and dying cells.
@en
Cell membrane permeabilization via connexin hemichannels in living and dying cells.
@nl
P2093
P1476
Cell membrane permeabilization via connexin hemichannels in living and dying cells.
@en
P2093
Juan A Orellana
Juan C Sáez
Kenji F Shoji
Michael V L Bennett
P304
P356
10.1016/J.YEXCR.2010.05.026
P407
P577
2010-06-02T00:00:00Z