Transglutaminase 2: a multi-tasking protein in the complex circuitry of inflammation and cancer.
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Tissue transglutaminase as a central mediator in inflammation-induced progression of breast cancerTransglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and deathCellular functions of tissue transglutaminasePhysiological, pathological, and structural implications of non-enzymatic protein-protein interactions of the multifunctional human transglutaminase 2Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cellsCompensatory Increase of Transglutaminase 2 Is Responsible for Resistance to mTOR Inhibitor TreatmentConformational changes and translocation of tissue-transglutaminase to the plasma membranes: role in cancer cell migration.Transglutaminase regulation of cell function.MTA1 coregulation of transglutaminase 2 expression and function during inflammatory response.Phosphorylation of transglutaminase 2 (TG2) at serine-216 has a role in TG2 mediated activation of nuclear factor-kappa B and in the downregulation of PTENTissue transglutaminase constitutively activates HIF-1α promoter and nuclear factor-κB via a non-canonical pathway.Characterization of distinct sub-cellular location of transglutaminase type II: changes in intracellular distribution in physiological and pathological statesTissue transglutaminase mediates the pro-malignant effects of oncostatin M receptor over-expression in cervical squamous cell carcinoma.Transglutaminase 2 and phospholipase A₂ interactions in the inflammatory response in human Thp-1 monocytes.Transglutaminase 2 overexpression in tumor stroma identifies invasive ductal carcinomas of breast at high risk of recurrence.Epidermal growth factor receptor-mediated tissue transglutaminase overexpression couples acquired tumor necrosis factor-related apoptosis-inducing ligand resistance and migration through c-FLIP and MMP-9 proteins in lung cancer cells.Novel 3-arylethynyl-substituted thieno[3,4-b]pyrazine derivatives as human transglutaminase 2 inhibitors.Macrophages in diabetic gastroparesis--the missing link?Mesenchymal stromal cells derived from acute myeloid leukemia bone marrow exhibit aberrant cytogenetics and cytokine elaboration.Transglutaminase 2: a molecular Swiss army knife.Transglutaminase Is Required for Epidermal Squamous Cell Carcinoma Stem Cell Survival.Transglutaminase 2 promotes both caspase-dependent and caspase-independent apoptotic cell death via the calpain/Bax protein signaling pathwayFission yeast Cyk3p is a transglutaminase-like protein that participates in cytokinesis and cell morphogenesis.RanBPM expression regulates transcriptional pathways involved in development and tumorigenesis.Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells.Tissue transglutaminase: a new target to reverse cancer drug resistanceTransglutaminase 2 cross-linking activity is linked to invadopodia formation and cartilage breakdown in arthritis.A comparison of epithelial-to-mesenchymal transition and re-epithelializationTissue transglutaminase-2 promotes gastric cancer progression via the ERK1/2 pathway.Transglutaminase 2 expression predicts progression free survival in non-small cell lung cancer patients treated with epidermal growth factor receptor tyrosine kinase inhibitorA nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells.Suppression of Transglutaminase-2 is Involved in Anti-Inflammatory Actions of Glucosamine in 12-O-Tetradecanoylphorbol-13-Acetate-Induced Skin Inflammation.Stromal Activation by Tumor Cells: An in Vitro Study in Breast CancerExpression of Transglutaminase in Foreskin of Children with Balanitis Xerotica ObliteransTumor macrophages are pivotal constructors of tumor collagenous matrix.Transglutaminse 2 and EGGL, the protein cross-link formed by transglutaminse 2, as therapeutic targets for disabilities of old age.Tissue transglutaminase-1 promotes stemness and chemoresistance in gastric cancer cells by regulating Wnt/β-catenin signaling.Methylglyoxal in cells elicits a negative feedback loop entailing transglutaminase 2 and glyoxalase 1.TG2, a novel extracellular protein with multiple functions.Transglutaminases and receptor tyrosine kinases.
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Transglutaminase 2: a multi-tasking protein in the complex circuitry of inflammation and cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 25 June 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Transglutaminase 2: a multi-ta ...... ry of inflammation and cancer.
@en
Transglutaminase 2: a multi-ta ...... ry of inflammation and cancer.
@nl
type
label
Transglutaminase 2: a multi-ta ...... ry of inflammation and cancer.
@en
Transglutaminase 2: a multi-ta ...... ry of inflammation and cancer.
@nl
prefLabel
Transglutaminase 2: a multi-ta ...... ry of inflammation and cancer.
@en
Transglutaminase 2: a multi-ta ...... ry of inflammation and cancer.
@nl
P2093
P1476
Transglutaminase 2: a multi-ta ...... ry of inflammation and cancer.
@en
P2093
Aupam Kumar
Hong Im Kim
Kapil Mehta
P304
P356
10.1016/J.BCP.2010.06.029
P407
P577
2010-06-25T00:00:00Z