Genomic profiling of high-risk acute lymphoblastic leukemia.
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The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia.Churchill: an ultra-fast, deterministic, highly scalable and balanced parallelization strategy for the discovery of human genetic variation in clinical and population-scale genomics.Mutations in the transmembrane and juxtamembrane domains enhance IL27R transforming activityUnderstanding the biology of CRLF2-overexpressing acute lymphoblastic leukemiaAbnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia.Advances in the Biology of Acute Lymphoblastic Leukemia-From Genomics to the ClinicIKZF1 deletion is associated with a poor outcome in pediatric B-cell precursor acute lymphoblastic leukemia in Japan.High CRLF2 expression associates with IKZF1 dysfunction in adult acute lymphoblastic leukemia without CRLF2 rearrangement.SNP array analysis in constitutional and cancer genome diagnostics--copy number variants, genotyping and quality control.Genome-wide arrays in routine diagnostics of hematological malignancies.Current and future management of Ph/BCR-ABL positive ALL.Clonal conversion of B lymphoid leukemia reveals cross-lineage transfer of malignant states.Molecular profiling of gene copy number abnormalities in key regulatory genes in high-risk B-lineage acute lymphoblastic leukemia: frequency and their association with clinicopathological findings in Indian patients.Mcm2 deficiency results in short deletions allowing high resolution identification of genes contributing to lymphoblastic lymphoma.Microarray-based genomic profiling as a diagnostic tool in acute lymphoblastic leukemia.An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions.Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome.IKZF1 and CRLF2 gene alterations correlate with poor prognosis in Japanese BCR-ABL1-negative high-risk B-cell precursor acute lymphoblastic leukemia.Section E6.1-6.4 of the ACMG technical standards and guidelines: chromosome studies of neoplastic blood and bone marrow-acquired chromosomal abnormalities.Newly diagnosed acute lymphoblastic leukemia in China (I): abnormal genetic patterns in 1346 childhood and adult cases and their comparison with the reports from Western countries.PAX5 alterations in genetically unclassified childhood Precursor B-cell acute lymphoblastic leukaemia.Impact of IKZF1 deletions and PAX5 amplifications in pediatric B-cell precursor ALL treated according to NOPHO protocols
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Genomic profiling of high-risk acute lymphoblastic leukemia.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 26 August 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Genomic profiling of high-risk acute lymphoblastic leukemia.
@en
Genomic profiling of high-risk acute lymphoblastic leukemia.
@nl
type
label
Genomic profiling of high-risk acute lymphoblastic leukemia.
@en
Genomic profiling of high-risk acute lymphoblastic leukemia.
@nl
prefLabel
Genomic profiling of high-risk acute lymphoblastic leukemia.
@en
Genomic profiling of high-risk acute lymphoblastic leukemia.
@nl
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P356
P1433
P1476
Genomic profiling of high-risk acute lymphoblastic leukemia
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P2093
J R Collins-Underwood
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P2888
P304
P356
10.1038/LEU.2010.177
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2010-08-26T00:00:00Z