Acid-sensing ion channels (ASICs): pharmacology and implication in pain.
about
Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransductionAcid-sensing ion channels in pain and disease.Structure and activity of the acid-sensing ion channelsIon channels as drug targets in central nervous system disordersRise of the sensors: nociception and pruritusASICs as therapeutic targets for migraineCiliated neurons lining the central canal sense both fluid movement and pH through ASIC3.Structural plasticity and dynamic selectivity of acid-sensing ion channel–spider toxin complexesSea Anemone Peptide with Uncommon -Hairpin Structure Inhibits Acid-sensing Ion Channel 3 (ASIC3) and Reveals Analgesic ActivityX-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective ChannelChemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2Menthol attenuates respiratory irritation responses to multiple cigarette smoke irritantsDifferential regulation of proton-sensitive ion channels by phospholipids: a comparative study between ASICs and TRPV1Neurosensory mechanotransduction through acid-sensing ion channelsHow we feel: ion channel partnerships that detect mechanical inputs and give rise to touch and pain perceptionThe Concise Guide to PHARMACOLOGY 2013/14: ion channelsPain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous κ-opioids.Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli.Targeting ASIC3 for Relieving Mice Fibromyalgia Pain: Roles of Electroacupuncture, Opioid, and Adenosine.Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin, V1A receptor in primary sensory neuronsProtons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala.Transient acidosis while retrieving a fear-related memory enhances its lability.Epigenetic modification of DRG neuronal gene expression subsequent to nerve injury: etiological contribution to complex regional pain syndromes (Part I).Roles of ASIC3, TRPV1, and NaV1.8 in the transition from acute to chronic pain in a mouse model of fibromyalgia.Drosophila nociceptors mediate larval aversion to dry surface environments utilizing both the painless TRP channel and the DEG/ENaC subunit, PPK1.Combining nitrous oxide with carbon dioxide decreases the time to loss of consciousness during euthanasia in mice--refinement of animal welfare?Receptor-targeting mechanisms of pain-causing toxins: How ow?Small molecule ion channel match making: a natural fit for new ASIC ligands.The pharmacology and therapeutic potential of small molecule inhibitors of acid-sensing ion channels in stroke interventionBinding site and inhibitory mechanism of the mambalgin-2 pain-relieving peptide on acid-sensing ion channel 1a.Cannabinoids inhibit acid-sensing ion channel currents in rat dorsal root ganglion neurons.Mechanisms of Myofascial PainAlgogenic substances and metabolic status in work-related Trapezius Myalgia: a multivariate explorative study.Loss of Acid sensing ion channel-1a and bicarbonate administration attenuate the severity of traumatic brain injuryPharmacogenetics of new analgesics.Effects of the triple monoamine uptake inhibitor amitifadine on pain-related depression of behavior and mesolimbic dopamine release in ratsDry needling - peripheral and central considerations.Acidic microenvironment and bone pain in cancer-colonized boneA heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce painNonproton ligand sensing domain is required for paradoxical stimulation of acid-sensing ion channel 3 (ASIC3) channels by amiloride.
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P2860
Acid-sensing ion channels (ASICs): pharmacology and implication in pain.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 31 August 2010
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Acid-sensing ion channels (ASICs): pharmacology and implication in pain.
@en
Acid-sensing ion channels
@nl
type
label
Acid-sensing ion channels (ASICs): pharmacology and implication in pain.
@en
Acid-sensing ion channels
@nl
prefLabel
Acid-sensing ion channels (ASICs): pharmacology and implication in pain.
@en
Acid-sensing ion channels
@nl
P2093
P1476
Acid-sensing ion channels (ASICs): pharmacology and implication in pain.
@en
P2093
Anne Baron
Emmanuel Deval
Eric Lingueglia
Jacques Noël
Miguel Salinas
Sylvie Diochot
Xavier Gasull
P304
P356
10.1016/J.PHARMTHERA.2010.08.006
P577
2010-08-31T00:00:00Z