Simvastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia.
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The role of statins as potential targets for bone formationA mechanistic, model-based approach to safety assessment in clinical developmentEfficacy of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors for prevention of stroke.Pharmacology of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins), including rosuvastatin and pitavastatin.Simvastatin Ameliorates Matrix Stiffness-Mediated Endothelial Monolayer Disruption.Cost-effectiveness of extended-release niacin/laropiprant added to a stable simvastatin dose in secondary prevention patients not at cholesterol goal in Germany.Benefits and risks assessment of simvastatin in familial hypercholesterolaemia.Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemiaLong-term safety of statin-fibrate combination treatment in the management of hypercholesterolaemia in patients with coronary artery disease.Hypolipidaemic Effect of Hericium erinaceum Grown in Artemisia capillaris on Obese Rats.The effect of local simvastatin delivery strategies on mandibular bone formation in vivo.Design of a multiple drug delivery system directed at periodontitisBioerodible system for sequential release of multiple drugs.Prevention approaches in a preclinical canine model of Alzheimer's disease: benefits and challenges.Clinical efficacy of subgingivally delivered simvastatin gel in chronic periodontitis patients.Targeting chronic inflammation in cerebral aneurysms: focusing on NF-kappaB as a putative target of medical therapy.Therapeutic interventions targeting Beta amyloid pathogenesis in an aging dog model.Systematic review of the in vitro effects of statins on oral and perioral microorganisms.Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway.The Effect of Locally Delivered Statins on Treating Periodontal Intrabony Defects: A Systematic Review and Meta-Analysis.Simvastatin combined with nifedipine enhances endothelial cell protection by inhibiting ROS generation and activating Akt phosphorylation.Comparative evaluation of the safety and efficacy of HMG-CoA reductase inhibitor monotherapy in the treatment of primary hypercholesterolemia.HDL heterogeneity and atherosclerosis.Fibrates and HMG-CoA reductase inhibitorsStatins: A new era in local drug deliveryStatins and "chameleon-like" cutaneous eruptions: simvastatin-induced acral cutaneous vesiculobullous and pustular eruption in a 70-year-old man.Simvastatin reduces sympathetic activity in men with hypertension and hypercholesterolemia.Clinical effect of subgingivally delivered simvastatin in the treatment of patients with chronic periodontitis: a randomized clinical trial.Development and Validation of an LC-MS-MS Method for Determination of Simvastatin and Simvastatin Acid in Human Plasma: Application to a Pharmacokinetic Study.
P2860
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P2860
Simvastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Simvastatin. A review of its p ...... tial in hypercholesterolaemia.
@en
Simvastatin. A review of its p ...... tial in hypercholesterolaemia.
@nl
type
label
Simvastatin. A review of its p ...... tial in hypercholesterolaemia.
@en
Simvastatin. A review of its p ...... tial in hypercholesterolaemia.
@nl
prefLabel
Simvastatin. A review of its p ...... tial in hypercholesterolaemia.
@en
Simvastatin. A review of its p ...... tial in hypercholesterolaemia.
@nl
P1433
P1476
Simvastatin. A review of its p ...... tial in hypercholesterolaemia.
@en
P304
P356
10.2165/00003495-199040040-00007
P577
1990-10-01T00:00:00Z
P6179
1034809086