ABC transporters and cytochromes P450 in the human central nervous system: influence on brain pharmacokinetics and contribution to neurodegenerative disorders.
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Nanotechnology: toxicologic pathologyPathobiology of tobacco smoking and neurovascular disorders: untied strings and alternative productsCytochrome P450-mediated drug metabolism in the brainGenetic dissection of strain dependent paraquat-induced neurodegeneration in the substantia nigra pars compacta.T-Lymphocyte Deficiency Exacerbates Behavioral Deficits in the 6-OHDA Unilateral Lesion Rat Model for Parkinson's Disease.Regulation of ABC transporters at the blood-brain barrier.In vitro blood-brain barrier models: current and perspective technologiesImproved Antidepressant Remission in Major Depression via a Pharmacokinetic Pathway Polygene Pharmacogenetic Report.Sex hormones regulate cerebral drug metabolism via brain miRNAs: down-regulation of brain CYP2D by androgens reduces the analgesic effects of tramadolSubacute nicotine co-exposure has no effect on 2,2',3,5',6- pentachlorobiphenyl disposition but alters hepatic cytochrome P450 expression in the male rat.Neurovascular dysfunction and faulty amyloid β-peptide clearance in Alzheimer disease.Characterization of passive permeability at the blood-tumor barrier in five preclinical models of brain metastases of breast cancer.A nutritional supplement containing lactoferrin stimulates the immune system, extends lifespan, and reduces amyloid β peptide toxicity in Caenorhabditis elegansEnvironmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics.Cytochrome P450-mediated metabolism in brain: functional roles and their implications.Blood-brain barrier structure and function and the challenges for CNS drug delivery.Improved brain uptake of peptide-based CNS drugs via alternative routes of administrations of its nanocarrier delivery systems: a promising strategy for CNS targeting delivery of peptides.Drug transporters in the central nervous system.Are the Current Guidelines on Caffeine Use in Sport Optimal for Everyone? Inter-individual Variation in Caffeine Ergogenicity, and a Move Towards Personalised Sports Nutrition.Role of neural barriers in the pathogenesis and outcome of Streptococcus pneumoniae meningitisDrug transport and metabolism in the blood-brain barrierRegulation of cerebral CYP2D alters tramadol metabolism in the brain: interactions of tramadol with propranolol and nicotine.ABCB1: is there a role in the drug treatment of Parkinson's disease?Differential Regulation of CYP3A4 and CYP3A5 and its Implication in Drug Discovery.Occurrence, distribution and potential actions of CYP2D6 in the brain
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P2860
ABC transporters and cytochromes P450 in the human central nervous system: influence on brain pharmacokinetics and contribution to neurodegenerative disorders.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2010
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
@cs
name
ABC transporters and cytochrom ...... o neurodegenerative disorders.
@en
ABC transporters and cytochrom ...... o neurodegenerative disorders.
@nl
type
label
ABC transporters and cytochrom ...... o neurodegenerative disorders.
@en
ABC transporters and cytochrom ...... o neurodegenerative disorders.
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prefLabel
ABC transporters and cytochrom ...... o neurodegenerative disorders.
@en
ABC transporters and cytochrom ...... o neurodegenerative disorders.
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P2093
P2860
P1476
ABC transporters and cytochrom ...... o neurodegenerative disorders.
@en
P2093
Aude Jacob
Fabien Dutheil
Marie-Anne Loriot
Philippe Beaune
Sandrine Dauchy
Xavier Declèves
P2860
P304
P356
10.1517/17425255.2010.510832
P407
P577
2010-10-01T00:00:00Z