20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension
about
Impact of soluble epoxide hydrolase and epoxyeicosanoids on human healthRole of the adenosine(2A) receptor-epoxyeicosatrienoic acid pathway in the development of salt-sensitive hypertensionInterlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids.Cytochrome P450 eicosanoids in hypertension and renal diseaseVascular actions of 20-HETE20-HETE and blood pressure regulation: clinical implicationsCYP4 enzymes as potential drug targets: focus on enzyme multiplicity, inducers and inhibitors, and therapeutic modulation of 20-hydroxyeicosatetraenoic acid (20-HETE) synthase and fatty acid ω-hydroxylase activitiesStabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancerEvaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular diseaseEpoxides and soluble epoxide hydrolase in cardiovascular physiologyCytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patientsInhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats20-HETE induces hyperglycemia through the cAMP/PKA-PhK-GP pathway.Epoxyeicosatrienoic Acids and 20-Hydroxyeicosatetraenoic Acid on Endothelial and Vascular Function.Identifying biomarkers for asthma diagnosis using targeted metabolomics approaches.Novel drugs targeting hypertension revisitedThe role of 20-HETE in androgen-mediated hypertension.Targeting 20-HETE producing enzymes in cancer - rationale, pharmacology, and clinical potentialAndrogen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.Cytochrome P4504A inhibitors attenuate the exaggerated natriuretic response to volume expansion in thyroidectomized rats.Determination of major UDP-glucuronosyltransferase enzymes and their genotypes responsible for 20-HETE glucuronidation.Androgen-induced hypertension in angiotensinogen deficient mice: role of 20-HETE and EETS20-Hydroxyeicosatetraenoic acid involved in endothelial activation and thrombosis.20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension.PharmGKB summary: very important pharmacogene information for CYP4F2Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive ratsEpoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures.Eicosanoids, β-cell function, and diabetesEETs Attenuate Ox-LDL-Induced LTB4 Production and Activity by Inhibiting p38 MAPK Phosphorylation and 5-LO/BLT1 Receptor Expression in Rat Pulmonary Arterial Endothelial Cells.Protection by 20-5,14-HEDGE against surgically induced ischemia reperfusion lung injury in rats.Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolaseAngiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertensionDetection of 19 types of para-arachidonic acids in five types of plasma/serum by ultra performance liquid chromatography-tandem mass spectrometry.The circadian clock modulates renal sodium handling.20-HETE contributes to ischemia-induced angiogenesis.Inhibitors of 20-hydroxyeicosatetraenoic acid (20-HETE) formation attenuate the natriuretic effect of dopamine.Soluble epoxide hydrolase null mice exhibit female and male differences in regulation of vascular homeostasisInhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.Cyclooxygenase-2 dependent metabolism of 20-HETE increases adiposity and adipocyte enlargement in mesenchymal stem cell-derived adipocytes.20-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition.
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20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on October 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension
@en
20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension.
@nl
type
label
20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension
@en
20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension.
@nl
prefLabel
20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension
@en
20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension.
@nl
P2093
P2860
P1476
20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension
@en
P2093
Jan M Williams
Marilyn Burke
Richard J Roman
Sydney Murphy
P2860
P304
P356
10.1097/FJC.0B013E3181F04B1C
P577
2010-10-01T00:00:00Z