20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension - Wikidata - wikimedia - TriplyDB

20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension

20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension

http://www.wikidata.org/entity/Q37798679

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Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health Role of the adenosine(2A) receptor-epoxyeicosatrienoic acid pathway in the development of salt-sensitive hypertension Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids.Cytochrome P450 eicosanoids in hypertension and renal disease Vascular actions of 20-HETE 20-HETE and blood pressure regulation: clinical implications CYP4 enzymes as potential drug targets: focus on enzyme multiplicity, inducers and inhibitors, and therapeutic modulation of 20-hydroxyeicosatetraenoic acid (20-HETE) synthase and fatty acid ω-hydroxylase activities Stabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancer Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease Epoxides and soluble epoxide hydrolase in cardiovascular physiology Cytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patients Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats 20-HETE induces hyperglycemia through the cAMP/PKA-PhK-GP pathway.Epoxyeicosatrienoic Acids and 20-Hydroxyeicosatetraenoic Acid on Endothelial and Vascular Function.Identifying biomarkers for asthma diagnosis using targeted metabolomics approaches.Novel drugs targeting hypertension revisited The role of 20-HETE in androgen-mediated hypertension.Targeting 20-HETE producing enzymes in cancer - rationale, pharmacology, and clinical potential Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.Cytochrome P4504A inhibitors attenuate the exaggerated natriuretic response to volume expansion in thyroidectomized rats.Determination of major UDP-glucuronosyltransferase enzymes and their genotypes responsible for 20-HETE glucuronidation.Androgen-induced hypertension in angiotensinogen deficient mice: role of 20-HETE and EETS 20-Hydroxyeicosatetraenoic acid involved in endothelial activation and thrombosis.20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension.PharmGKB summary: very important pharmacogene information for CYP4F2 Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures.Eicosanoids, β-cell function, and diabetes EETs Attenuate Ox-LDL-Induced LTB4 Production and Activity by Inhibiting p38 MAPK Phosphorylation and 5-LO/BLT1 Receptor Expression in Rat Pulmonary Arterial Endothelial Cells.Protection by 20-5,14-HEDGE against surgically induced ischemia reperfusion lung injury in rats.Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension Detection of 19 types of para-arachidonic acids in five types of plasma/serum by ultra performance liquid chromatography-tandem mass spectrometry.The circadian clock modulates renal sodium handling.20-HETE contributes to ischemia-induced angiogenesis.Inhibitors of 20-hydroxyeicosatetraenoic acid (20-HETE) formation attenuate the natriuretic effect of dopamine.Soluble epoxide hydrolase null mice exhibit female and male differences in regulation of vascular homeostasis Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.Cyclooxygenase-2 dependent metabolism of 20-HETE increases adiposity and adipocyte enlargement in mesenchymal stem cell-derived adipocytes.20-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition.

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20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension

http://www.wikidata.org/entity/Q37798679

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on October 2010

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension

@en

20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension.

@nl

type

label

20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension

@en

20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension.

@nl

prefLabel

20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension

@en

20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension.

@nl

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FJC.0B013E3181F04B1C

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Journal of Cardiovascular Pharmacology

P1476

20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension

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P2093

Jan M Williams

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Marilyn Burke

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Richard J Roman

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Sydney Murphy

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P2860

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11

Functional polymorphism in human CYP4F2 decreases 20-HETE production

A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure

Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11

Association of the T8590C polymorphism of CYP4A11 with hypertension in the MONICA Augsburg echocardiographic substudy

Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases

Association of common variants of CYP4A11 and CYP4F2 with stroke in the Han Chinese population

Association of a CYP4A11 variant and blood pressure in black men

A polymorphism regulates CYP4A11 transcriptional activity and is associated with hypertension in a Japanese population

Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension

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336-344

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scholarly article

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10.1097/FJC.0B013E3181F04B1C

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4

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56

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2010-10-01T00:00:00Z

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20930591

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P921

arterial hypertension

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2953733

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