Hereditary spastic paraplegias: membrane traffic and the motor pathway.
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The fifth adaptor protein complexMutations in the ER-shaping protein reticulon 2 cause the axon-degenerative disorder hereditary spastic paraplegia type 12Hereditary spastic paraplegia type 43 (SPG43) is caused by mutation in C19orf12Loss of association of REEP2 with membranes leads to hereditary spastic paraplegiaProtrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formationMutation in CPT1C Associated With Pure Autosomal Dominant Spastic ParaplegiaThe retromer complex - endosomal protein recycling and beyondThe axonal transport of mitochondriaQuantitative Gait Analysis Using a Motorized Treadmill System Sensitively Detects Motor Abnormalities in Mice Expressing ATPase Defective SpastinSpastic paraplegia mutation N256S in the neuronal microtubule motor KIF5A disrupts axonal transport in a Drosophila HSP modelHereditary spastic paraplegia SPG4: what is known and not known about the disease.REEPs are membrane shaping adapter proteins that modulate specific g protein-coupled receptor trafficking by affecting ER cargo capacitySpg20-/- mice reveal multimodal functions for Troyer syndrome protein spartin in lipid droplet maintenance, cytokinesis and BMP signalingSpastic paraplegia type 7 is associated with multiple mitochondrial DNA deletionsThree routes to suppression of the neurodegenerative phenotypes caused by kinesin heavy chain mutationsMicrotubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice.Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure.An ESCRT-spastin interaction promotes fission of recycling tubules from the endosome.A spastic paraplegia mouse model reveals REEP1-dependent ER shaping.Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegiaLysosomal abnormalities in hereditary spastic paraplegia types SPG15 and SPG11.Axonal transport plays a crucial role in mediating the axon-protective effects of NmNATTargeted high-throughput sequencing identifies mutations in atlastin-1 as a cause of hereditary sensory neuropathy type I.A new mouse allele of glutamate receptor delta 2 with cerebellar atrophy and progressive ataxia.Alternative splicing of Spg7, a gene involved in hereditary spastic paraplegia, encodes a variant of paraplegin targeted to the endoplasmic reticulum.Transcriptional and post-transcriptional regulation of SPAST, the gene most frequently mutated in hereditary spastic paraplegia.Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A.Alteration of fatty-acid-metabolizing enzymes affects mitochondrial form and function in hereditary spastic paraplegia.Phosphoinositides differentially regulate protrudin localization through the FYVE domainFine-scale linkage mapping reveals a small set of candidate genes influencing honey bee grooming behavior in response to Varroa mites.Retinal nerve fibre layer loss in hereditary spastic paraplegias is restricted to complex phenotypes.Spastin-interacting protein NA14/SSNA1 functions in cytokinesis and axon development.Hyperglycemia- and neuropathy-induced changes in mitochondria within sensory nerves.A novel homozygous p.R1105X mutation of the AP4E1 gene in twins with hereditary spastic paraplegia and mycobacterial disease.Fusing a lasting relationship between ER tubules.Balancing ER dynamics: shaping, bending, severing, and mending membranesAging and functional brain networks.A nullimorphic ERLIN2 mutation defines a complicated hereditary spastic paraplegia locus (SPG18)Strumpellin and Spartin, Hereditary Spastic Paraplegia Proteins, are Binding Partners.
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Hereditary spastic paraplegias: membrane traffic and the motor pathway.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Hereditary spastic paraplegias: membrane traffic and the motor pathway.
@en
Hereditary spastic paraplegias: membrane traffic and the motor pathway.
@nl
type
label
Hereditary spastic paraplegias: membrane traffic and the motor pathway.
@en
Hereditary spastic paraplegias: membrane traffic and the motor pathway.
@nl
prefLabel
Hereditary spastic paraplegias: membrane traffic and the motor pathway.
@en
Hereditary spastic paraplegias: membrane traffic and the motor pathway.
@nl
P2860
P356
P1476
Hereditary spastic paraplegias: membrane traffic and the motor pathway.
@en
P2093
Craig Blackstone
P2860
P2888
P356
10.1038/NRN2946
P407
P577
2011-01-01T00:00:00Z