Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications.
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Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac deathMarkov models of use-dependence and reverse use-dependence during the mouse cardiac action potentialA compartmentalized mathematical model of the β1-adrenergic signaling system in mouse ventricular myocytesImproved functional expression of human cardiac kv1.5 channels and trafficking-defective mutants by low temperature treatmentThe mechanisms of calcium cycling and action potential dynamics in cardiac alternansNovel pharmacological targets for the rhythm control management of atrial fibrillation.Atrial-selective sodium channel block strategy to suppress atrial fibrillation: ranolazine versus propafenone.A Regional Reduction in Ito and IKACh in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity.Atrial-selective prolongation of refractory period with AVE0118 is due principally to inhibition of sodium channel activity.PKC and AMPK regulation of Kv1.5 potassium channelsL-Type Calcium Channel Inhibition Contributes to the Proarrhythmic Effects of Aconitine in Human Cardiomyocytes.Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial fibrillation.Effects of IKur blocker MK-0448 on human right atrial action potentials from patients in sinus rhythm and in permanent atrial fibrillationAtrial remodeling in atrial fibrillation and association between microRNA network and atrial fibrillation.Novel molecular targets for atrial fibrillation therapy.Potassium channels in Drosophila: historical breakthroughs, significance, and perspectives.Atrial selectivity of antiarrhythmic drugs.Identifying potential functional impact of mutations and polymorphisms: linking heart failure, increased risk of arrhythmias and sudden cardiac deathThe role of the cytosolic HSP70 chaperone system in diseases caused by misfolding and aberrant trafficking of ion channelsCardiac potassium channel subtypes: new roles in repolarization and arrhythmia.The positive frequency-dependent electrophysiological effects of the IKur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation.Alternans in atria: Mechanisms and clinical relevance.High fat diet induced alterations of atrial electrical activities in mice.Inhibitory effects of cholinesterase inhibitor donepezil on the Kv1.5 potassium channel.Putative binding sites for arachidonic acid on the human cardiac Kv 1.5 channel.Atrial-selective inhibition of sodium-channel current by Wenxin Keli is effective in suppressing atrial fibrillation.Inhibition of a TREK-like K+ channel current by noradrenaline requires both β1- and β2-adrenoceptors in rat atrial myocytes.Revealing kinetics and state-dependent binding properties of IKur-targeting drugs that maximize atrial fibrillation selectivity.PKC inhibition results in a Kv 1.5 + Kv β1.3 pharmacology closer to Kv 1.5 channels.Multi-channel blockers for treatment of atrial fibrillation: an effective strategy?Pergolide block of the cloned Kv1.5 potassium channels.Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K+ channel Kv1.5.Synergistic Anti-arrhythmic Effects in Human Atria with Combined Use of Sodium Blockers and Acacetin.Taurine Prevents the Electrical Remodeling in Ach-CaCl2 Induced Atrial Fibrillation in Rats.Inhibition of Kv4.3 potassium channels by trazodone.Isoenzyme-specific regulation of cardiac Kv1.5/Kvβ1.2 ion channel complex by protein kinase C: central role of PKCβII.Regulation of human cardiac Kv1.5 channels by extracellular acidification.Enhancement of 5-HT2A receptor function and blockade of Kv1.5 by MK801 and ketamine: implications for PCP derivative-induced disease models.Generation and customization of biosynthetic excitable tissues for electrophysiological studies and cell-based therapies.Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges
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P2860
Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 December 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications.
@en
Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications.
@nl
type
label
Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications.
@en
Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications.
@nl
prefLabel
Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications.
@en
Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications.
@nl
P2860
P356
P1476
Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications.
@en
P2093
Erich Wettwer
Ursula Ravens
P2860
P304
P356
10.1093/CVR/CVQ398
P577
2010-12-15T00:00:00Z