The structural basis for deadenylation by the CCR4-NOT complex. - Wikidata - wikimedia - TriplyDB

The structural basis for deadenylation by the CCR4-NOT complex.

The structural basis for deadenylation by the CCR4-NOT complex.

http://www.wikidata.org/entity/Q37825827

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The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain The role of the CNOT1 subunit of the CCR4-NOT complex in mRNA deadenylation and cell viability Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity Structural basis for inhibition of the deadenylase activity of human CNOT6L hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.Insights into the structure and architecture of the CCR4-NOT complex Novel roles of the multi-functional CCR4-NOT complex in post-transcriptional regulation.Uncoupling of mRNA synthesis and degradation impairs adaptation to host temperature in Cryptococcus neoformans Multifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.Interaction of NANOS2 and NANOS3 with different components of the CNOT complex may contribute to the functional differences in mouse male germ cells.A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity.Cantharidin represses invasion of pancreatic cancer cells through accelerated degradation of MMP2 mRNA.Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse.CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins Function of Nanos1 gene in the development of reproductive organs of Schistosoma japonicum.HIPK family kinases bind and regulate the function of the CCR4-NOT complex.Stability of mRNA influences osteoporotic bone mass via CNOT3.Deadenylation of cytoplasmic mRNA by the mammalian Ccr4-Not complex.Identification of Ccr4-not complex components as regulators of transition from partial to genuine induced pluripotent stem cells.The Not4 E3 ligase and CCR4 deadenylase play distinct roles in protein quality control.The Ccr4-Not Complex: Architecture and Structural Insights.

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The structural basis for deadenylation by the CCR4-NOT complex.

http://www.wikidata.org/entity/Q37825827

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on May 2010

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

The structural basis for deadenylation by the CCR4-NOT complex.

@en

The structural basis for deadenylation by the CCR4-NOT complex.

@nl

type

label

The structural basis for deadenylation by the CCR4-NOT complex.

@en

The structural basis for deadenylation by the CCR4-NOT complex.

@nl

prefLabel

The structural basis for deadenylation by the CCR4-NOT complex.

@en

The structural basis for deadenylation by the CCR4-NOT complex.

@nl

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The structural basis for deadenylation by the CCR4-NOT complex.

@en

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Mark Bartlam

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Tadashi Yamamoto

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P2860

Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding

Human carbon catabolite repressor protein (CCR4)-associative factor 1: cloning, expression and characterization of its interaction with the B-cell translocation protein BTG1

The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activation

Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.

Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1, the human homolog of a component of the yeast CCR4 transcriptional complex: involvement in estrogen receptor alpha signaling pathway

Functional organization of the yeast proteome by systematic analysis of protein complexes

CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase.

Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth

The BTG2 protein is a general activator of mRNA deadenylation

Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex

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s13238-010-0060-8

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443-452

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scholarly article

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10.1007/S13238-010-0060-8

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2010-05-01T00:00:00Z

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4875137

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