Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness.
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Altered expression of stromal interaction molecule (STIM)-calcium release-activated calcium channel protein (ORAI) and inositol 1,4,5-trisphosphate receptors (IP3Rs) in cancer: will they become a new battlefield for oncotherapy?Peptide Hydrogels - Versatile Matrices for 3D Cell Culture in Cancer MedicinePhysical biology in cancer. 5. The rocky road of metastasis: the role of cytoskeletal mechanics in cell migratory response to 3D matrix topographyDeconstructing the third dimension: how 3D culture microenvironments alter cellular cuesThe platelet and the biophysical microenvironment: lessons from cellular mechanicsTumor cell migration in complex microenvironmentsA quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotypeContribution of soft substrates to malignancy and tumor suppression during colon cancer cell divisionMicrorheological characterization of collagen systems: from molecular solutions to fibrillar gelsPhenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironmentMicrofabricated physical spatial gradients for investigating cell migration and invasion dynamicsA serial micropipette microfluidic device with applications to cancer cell repeated deformation studies.From molecular signal activation to locomotion: an integrated, multiscale analysis of cell motility on defined matricesSingle-Cell Migration in Complex Microenvironments: Mechanics and Signaling DynamicsMatrix microarchitecture and myosin II determine adhesion in 3D matrices.Interstitial fluid flow in cancer: implications for disease progression and treatment.Nanoimaging of focal adhesion dynamics in 3DTransforming potential and matrix stiffness co-regulate confinement sensitivity of tumor cell migrationAutomated, contour-based tracking and analysis of cell behaviour over long time scales in environments of varying complexity and cell density.A mechanically-induced colon cancer cell population shows increased metastatic potential.Concentration independent modulation of local micromechanics in a fibrin gel.Two-way regulation between cells and aligned collagen fibrils: local 3D matrix formation and accelerated neural differentiation of human decidua parietalis placental stem cellsCollective and individual migration following the epithelial-mesenchymal transition.Attenuation of cell mechanosensitivity in colon cancer cells during in vitro metastasisMicroscale mechanisms of agarose-induced disruption of collagen remodeling.Constitutive activation of myosin-dependent contractility sensitizes glioma tumor-initiating cells to mechanical inputs and reduces tissue invasionPatterned polymer matrix promotes stemness and cell-cell interaction of adult stem cells.Toward single cell traction microscopy within 3D collagen matrices.Biophysical control of invasive tumor cell behavior by extracellular matrix microarchitecture.Free Form Deformation-Based Image Registration Improves Accuracy of Traction Force Microscopy.Independent regulation of tumor cell migration by matrix stiffness and confinement.Soft fibrin gels promote selection and growth of tumorigenic cells.Cancer cell migration within 3D layer-by-layer microfabricated photocrosslinked PEG scaffolds with tunable stiffness.Interstitial flows promote amoeboid over mesenchymal motility of breast cancer cells revealed by a three dimensional microfluidic model.The role of myosin II in glioma invasion: A mathematical model.Characterization of three-dimensional cancer cell migration in mixed collagen-Matrigel scaffolds using microfluidics and image analysis.Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments.Topographic confinement of epithelial clusters induces epithelial-to-mesenchymal transition in compliant matricesLeading malignant cells initiate collective epithelial cell invasion in a three-dimensional heterotypic tumor spheroid modelCollective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local softening
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Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 06 January 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness.
@en
Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness.
@nl
type
label
Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness.
@en
Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness.
@nl
prefLabel
Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness.
@en
Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness.
@nl
P2860
P356
P1433
P1476
Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness
@en
P2093
Sanjay Kumar
P2860
P304
P356
10.1039/C0IB00095G
P50
P577
2011-01-06T00:00:00Z