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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)A fast and simple method for simultaneous mixed site-specific mutagenesis of a wide coding sequence.Epigenetic control of autophagy by microRNAs in ovarian cancerAutophagy Correlates with the Therapeutic Responsiveness of Malignant Pleural Mesothelioma in 3D Models.Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma.Age-related oxidative stress compromises endosomal proteostasis.Biocompatibility, endocytosis, and intracellular trafficking of mesoporous silica and polystyrene nanoparticles in ovarian cancer cells: effects of size and surface charge groups.Role of Carbonyl Modifications on Aging-Associated Protein Aggregation.Autophagy initiation correlates with the autophagic flux in 3D models of mesothelioma and with patient outcome.High expression of cathepsin D in non-Hodgkin's lymphomas negatively impacts on clinical outcome.The dilemma: does tissue expression of cathepsin D reflect tumor malignancy? The question: does the assay truly mirror cathepsin D mis-function in the tumor?Oxidative stress, inflamm-aging and immunosenescence.The protein restriction mimetic Resveratrol is an autophagy inducer stronger than amino acid starvation in ovarian cancer cells.The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders.PTEN regulates plasma membrane expression of glucose transporter 1 and glucose uptake in thyroid cancer cells.Turmeric toxicity in A431 epidermoid cancer cells associates with autophagy degradation of anti-apoptotic and anti-autophagic p53 mutant.PTEN dephosphorylates AKT to prevent the expression of GLUT1 on plasmamembrane and to limit glucose consumption in cancer cellsSimilarities and differences in the biogenesis, processing and lysosomal targeting between zebrafish and human pro-Cathepsin D: functional implications.Dopamine induces apoptosis in APPswe-expressing Neuro2A cells following Pepstatin-sensitive proteolysis of APP in acid compartments.Knockdown of cathepsin D in zebrafish fertilized eggs determines congenital myopathy.Inhibition of PI3k class III-dependent autophagy prevents apoptosis and necrosis by oxidative stress in dopaminergic neuroblastoma cells.Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine.Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes.Cathepsin D-Bax death pathway in oxidative stressed neuroblastoma cells.Folding, activity and targeting of mutated human cathepsin D that cannot be processed into the double-chain form.Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D.High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells.PTEN deficiency and mutant p53 confer glucose-addiction to thyroid cancer cells: impact of glucose depletion on cell proliferation, cell survival, autophagy and cell migration.Inhibition of autophagy initiation potentiates chemosensitivity in mesothelioma.Autophagy-active beclin-1 correlates with favourable clinical outcome in non-Hodgkin lymphomasGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy facilitates the release of immunogenic signals following chemotherapy in 3D models of mesothelioma
P50
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P50
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P106
P21
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